Cheng Xian-Long, Ma Shuang-Cheng, Wei Feng, Wang Gang-Li, Xiao Xin-Yue, Lin Rui-Chao
Department of Chinese Materia Medica and Natural Products, National Institute for the Control of Pharmaceutical and Biological Products, Beijing, PR China.
Chem Pharm Bull (Tokyo). 2007 Sep;55(9):1390-2. doi: 10.1248/cpb.55.1390.
A new sesquiterpene, neolindenenonelactone (1), was first isolated from the dried roots of Lindera aggregata (SIMS) KOSTERM., along with four known compounds, linderane (2), isolinderalactone (3), linderalactone (4), and 8-hydroxylindestenolide (5). Their chemical structures were elucidated using spectral analysis of fast atom bombardment mass spectroscopy, one-dimensional nuclear magnetic resonance spectroscopy and two-dimensional-nuclear magnetic resonance spectroscopy including (1)H-NMR, (13)C-NMR, distortionless enhancement by polarization transfer, heteronuclear multiple-bond coherence, and single-crystal X-ray diffraction techniques.
一种新的倍半萜，新乌药内酯（1），首次从乌药（Lindera aggregata (SIMS) KOSTERM.）的干燥根中分离得到，同时还分离出四种已知化合物，乌药烷（2）、异乌药内酯（3）、乌药内酯（4）和8-羟基乌药内酯（5）。通过快原子轰击质谱、一维核磁共振光谱和二维核磁共振光谱（包括（1）H-NMR、（13）C-NMR、极化转移无畸变增强、异核多键相干）的光谱分析以及单晶X射线衍射技术对它们的化学结构进行了阐明。
