A review on the chemical constituents and pharmacological efficacies of (Sims) Kosterm.

(Sims) Kosterm. (), which belongs to the genus in the family Lauraceae, is widely distributed in Asia and the temperate, tropical regions of North America. Its roots and leaves have been used for thousands of years as traditional Chinese medicine and/or functional food. To further explore its underlying nutritional value, this review provided a comprehensive insight into chemical constituents and pharmacological effects on . The phytochemical investigation of different parts of led to the identification of up to 349 components belonging to sesquiterpenoids, alkaloids, flavonoids, essential oils, and other compounds. Among them, sesquiterpenoids, flavonoids, and alkaloids are assessed as representative active ingredients of . A wide variety of pharmacological effects of , such as anti-hyperlipidemic, anti-tumor, anti-inflammatory, analgesic, and anti-oxidant, have been proved and . In summary, this review aims to provide a scientific basis and reference for further research and utilization of and lay the foundation for developing functional foods with potential active ingredients for the prevention and management of related diseases.