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产后抑郁症与11岁儿童的结局:准确诊断的重要性。

Postnatal depression and child outcome at 11 years: the importance of accurate diagnosis.

作者信息

Pawlby Susan, Sharp Deborah, Hay Dale, O'Keane Veronica

机构信息

Institute of Psychiatry, King's College, London, UK.

出版信息

J Affect Disord. 2008 Apr;107(1-3):241-5. doi: 10.1016/j.jad.2007.08.002. Epub 2007 Sep 12.

DOI:10.1016/j.jad.2007.08.002
PMID:17854906
Abstract

BACKGROUND

One in ten women suffers from postnatal depression (PND) and their children have elevated rates of psychopathology. We compared caseness of PND using the Edinburgh Postnatal Depression Scale (EPDS), the most commonly used research tool for the detection of PND, and the Clinical Interview Schedule (CIS) in terms of their relative abilities to identify infants at risk of psychopathology in middle childhood.

METHOD

In a prospective longitudinal primary care study, 147 randomly selected women were administered both the CIS and the EPDS at three months postpartum. Childhood psychopathology was identified by face-to-face interview at 11 years.

RESULTS

The risk for psychiatric disorder at 11 years was four times greater among children whose mothers were cases of PND on the CIS, compared to children whose mothers were not depressed. Using the EPDS to identify PND, there was no significant difference in the risk for children whose mothers scored above and below a conventional cut-off score.

LIMITATIONS

This study was retrospectively designed and was not part of the original study plan.

CONCLUSIONS

These data support the evidence that accurate detection of PND is better achieved by face-to-face clinical interview than through the use of the EPDS. They provide novel evidence that a simple diagnostic clinical interview for PND, in contrast to the EPDS, can identify mothers whose children will be at an increased risk of developing psychiatric disorder in later childhood.

摘要

背景

十分之一的女性患有产后抑郁症(PND),其子女出现精神病理学问题的几率更高。我们比较了使用爱丁堡产后抑郁量表(EPDS,检测产后抑郁症最常用的研究工具)和临床访谈问卷(CIS)诊断产后抑郁症的情况,看它们在识别童年中期有精神病理学风险的儿童方面的相对能力。

方法

在一项前瞻性纵向初级保健研究中,147名随机挑选的女性在产后三个月时同时接受了CIS和EPDS测试。在这些儿童11岁时通过面对面访谈确定其童年期精神病理学情况。

结果

与母亲未患抑郁症的儿童相比,母亲在CIS测试中被诊断为产后抑郁症的儿童在11岁时患精神疾病的风险高出四倍。使用EPDS来识别产后抑郁症时,母亲得分高于和低于传统临界值的儿童在患病风险上没有显著差异。

局限性

本研究为回顾性设计,并非原始研究计划的一部分。

结论

这些数据支持以下证据,即通过面对面临床访谈比使用EPDS能更好地准确检测产后抑郁症。它们提供了新的证据,即与EPDS不同,一个简单的产后抑郁症诊断临床访谈能够识别出其子女在童年后期患精神疾病风险增加的母亲。

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