苯甲酸对酿酒酵母糖酵解代谢物水平及细胞内pH的影响。
Effect of benzoic acid on glycolytic metabolite levels and intracellular pH in Saccharomyces cerevisiae.
作者信息
Warth A D
机构信息
Division of Food Processing, Commonwealth Scientific and Industrial Research Organization, North Ryde, New South Wales, Australia.
出版信息
Appl Environ Microbiol. 1991 Dec;57(12):3415-7. doi: 10.1128/aem.57.12.3415-3417.1991.
Abstract
Low concentrations of benzoic acid stimulated fermentation rates in Saccharomyces cerevisiae. At concentrations near the maximum permitting growth, there was inhibition of fermentation, lowered ATP and intracellular pH, and relatively greater accumulation of benzoate. Changes in the levels of glycolytic intermediates suggested that fermentation was inhibited as a result of high ATP usage rather than of lowered intracellular pH. Specific inhibition of phosphofructokinase or of several other glycolytic enzymes was not observed.
摘要
低浓度的苯甲酸刺激了酿酒酵母的发酵速率。在接近最大允许生长浓度时，发酵受到抑制，ATP和细胞内pH值降低，苯甲酸积累相对更多。糖酵解中间产物水平的变化表明，发酵受到抑制是由于ATP消耗量大，而非细胞内pH值降低。未观察到磷酸果糖激酶或其他几种糖酵解酶的特异性抑制作用。
相似文献
1
Effect of benzoic acid on glycolytic metabolite levels and intracellular pH in Saccharomyces cerevisiae.苯甲酸对酿酒酵母糖酵解代谢物水平及细胞内pH的影响。
Appl Environ Microbiol. 1991 Dec;57(12):3415-7. doi: 10.1128/aem.57.12.3415-3417.1991.
2
Mechanism of action of benzoic acid on Zygosaccharomyces bailii: effects on glycolytic metabolite levels, energy production, and intracellular pH.苯甲酸对拜耳接合酵母的作用机制：对糖酵解代谢物水平、能量产生和细胞内pH的影响。
Appl Environ Microbiol. 1991 Dec;57(12):3410-4. doi: 10.1128/aem.57.12.3410-3414.1991.
3
Studies on the mechanism of the antifungal action of benzoate.苯甲酸盐抗真菌作用机制的研究。
Biochem J. 1983 Sep 15;214(3):657-63. doi: 10.1042/bj2140657.
4
Metabolic effects of benzoate and sorbate in the yeast Saccharomyces cerevisiae at neutral pH.苯甲酸酯和山梨酸酯在中性pH值下对酿酒酵母的代谢影响。
Arch Microbiol. 1993;159(3):220-4. doi: 10.1007/BF00248475.
5
Effect of benzoic acid on metabolic fluxes in yeasts: a continuous-culture study on the regulation of respiration and alcoholic fermentation.苯甲酸对酵母代谢通量的影响：关于呼吸作用和酒精发酵调节的连续培养研究
Yeast. 1992 Jul;8(7):501-17. doi: 10.1002/yea.320080703.
6
Inhibition of glycolysis by 2-deoxygalactose in Saccharomyces cerevisiae.2-脱氧半乳糖对酿酒酵母糖酵解的抑制作用。
Yeast. 1992 Feb;8(2):107-15. doi: 10.1002/yea.320080205.
7
Effects of m-Cl-peroxy benzoic acid on glycolysis in Saccharomyces cerevisiae.
Arch Microbiol. 1985 Dec;143(3):220-4. doi: 10.1007/BF00411239.
8
Effect of benzoate on the metabolism of fructose 2,6-bisphosphate in yeast.苯甲酸盐对酵母中果糖2,6 -二磷酸代谢的影响。
Eur J Biochem. 1986 Jan 2;154(1):141-5. doi: 10.1111/j.1432-1033.1986.tb09369.x.
9
Dynamic in vivo metabolome response of Saccharomyces cerevisiae to a stepwise perturbation of the ATP requirement for benzoate export.酿酒酵母对苯甲酸输出所需ATP逐步扰动的动态体内代谢组反应。
Biotechnol Bioeng. 2008 Feb 1;99(2):421-41. doi: 10.1002/bit.21557.
10
Growth characteristics of Saccharomyces cerevisiae S288C in changing environmental conditions: auxo-accelerostat study.酿酒酵母S288C在变化环境条件下的生长特性：营养缺陷型恒化器研究
Antonie Van Leeuwenhoek. 2007 Jul;92(1):109-28. doi: 10.1007/s10482-007-9141-y. Epub 2007 Feb 1.
引用本文的文献
1
Effects of benzoic and cinnamic acids on growth, mineral composition, and chlorophyll content of soybean.苯甲酸和肉桂酸对大豆生长、矿物质组成和叶绿素含量的影响。
J Chem Ecol. 1994 Nov;20(11):2821-33. doi: 10.1007/BF02098391.
2
Adaptive response and tolerance to weak acids in Saccharomyces cerevisiae: a genome-wide view.酿酒酵母对弱酸的适应性反应和耐受性：全基因组视角。
OMICS. 2010 Oct;14(5):525-40. doi: 10.1089/omi.2010.0072.
3
Seed Dormancy in Red Rice (Oryza sativa) (IX. Embryo Fructose-2,6-Bisphosphate during Dormancy Breaking and Subsequent Germination).红米（水稻）种子的休眠（IX. 休眠破除及随后萌发过程中的胚果糖-2,6-二磷酸）
Plant Physiol. 1995 Apr;107(4):1365-1370. doi: 10.1104/pp.107.4.1365.
4
The H(+)-ATPase in the plasma membrane of Saccharomyces cerevisiae is activated during growth latency in octanoic acid-supplemented medium accompanying the decrease in intracellular pH and cell viability.在添加辛酸的培养基中，酿酒酵母质膜中的H(+)-ATP酶在生长潜伏期被激活，同时细胞内pH值和细胞活力下降。
Appl Environ Microbiol. 1998 Feb;64(2):779-83. doi: 10.1128/AEM.64.2.779-783.1998.
5
Measurement of the effects of acetic acid and extracellular pH on intracellular pH of nonfermenting, individual Saccharomyces cerevisiae cells by fluorescence microscopy.通过荧光显微镜测量乙酸和细胞外pH对非发酵型单个酿酒酵母细胞内pH的影响。
Appl Environ Microbiol. 1998 Feb;64(2):530-4. doi: 10.1128/AEM.64.2.530-534.1998.
6
Energy-dependent, carrier-mediated extrusion of carboxyfluorescein from Saccharomyces cerevisiae allows rapid assessment of cell viability by flow cytometry.依赖能量的、载体介导的羧基荧光素从酿酒酵母中的外排使得通过流式细胞术快速评估细胞活力成为可能。
Appl Environ Microbiol. 1994 May;60(5):1467-72. doi: 10.1128/aem.60.5.1467-1472.1994.
7
Mechanisms of membrane toxicity of hydrocarbons.碳氢化合物的膜毒性机制。
Microbiol Rev. 1995 Jun;59(2):201-22. doi: 10.1128/mr.59.2.201-222.1995.
8
Isolation and characterization of acetic acid-tolerant galactose-fermenting strains of Saccharomyces cerevisiae from a spent sulfite liquor fermentation plant.从亚硫酸盐废液发酵厂分离并鉴定耐乙酸的酿酒酵母半乳糖发酵菌株。
Appl Environ Microbiol. 1992 May;58(5):1661-9. doi: 10.1128/aem.58.5.1661-1669.1992.
本文引用的文献
1
Effect of benzoic Acid on growth yield of yeasts differing in their resistance to preservatives.苯甲酸对不同防腐剂抗性酵母生长产量的影响。
Appl Environ Microbiol. 1988 Aug;54(8):2091-5. doi: 10.1128/aem.54.8.2091-2095.1988.
2
Studies on the mechanism of the antifungal action of benzoate.苯甲酸盐抗真菌作用机制的研究。
Biochem J. 1983 Sep 15;214(3):657-63. doi: 10.1042/bj2140657.
3
Concentrations of intermediary metabolites in yeast.酵母中中间代谢产物的浓度。
Biochimie. 1973;55(2):205-11. doi: 10.1016/s0300-9084(73)80393-1.
4
Relationships between the resistance of yeasts to acetic, propanoic and benzoic acids and to methyl paraben and pH.
Int J Food Microbiol. 1989 Jul;8(4):343-9. doi: 10.1016/0168-1605(89)90005-6.
5
Mechanism of action of benzoic acid on Zygosaccharomyces bailii: effects on glycolytic metabolite levels, energy production, and intracellular pH.苯甲酸对拜耳接合酵母的作用机制：对糖酵解代谢物水平、能量产生和细胞内pH的影响。
Appl Environ Microbiol. 1991 Dec;57(12):3410-4. doi: 10.1128/aem.57.12.3410-3414.1991.
6
Physiological effects of seven different blocks in glycolysis in Saccharomyces cerevisiae.酿酒酵母中糖酵解的七种不同阻断的生理效应。
J Bacteriol. 1979 Jul;139(1):152-60. doi: 10.1128/jb.139.1.152-160.1979.
Zotero 插件