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本文引用的文献

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Effect of benzoic Acid on growth yield of yeasts differing in their resistance to preservatives.苯甲酸对不同防腐剂抗性酵母生长产量的影响。
Appl Environ Microbiol. 1988 Aug;54(8):2091-5. doi: 10.1128/aem.54.8.2091-2095.1988.
2
Studies on the mechanism of the antifungal action of benzoate.苯甲酸盐抗真菌作用机制的研究。
Biochem J. 1983 Sep 15;214(3):657-63. doi: 10.1042/bj2140657.
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Concentrations of intermediary metabolites in yeast.酵母中中间代谢产物的浓度。
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Relationships between the resistance of yeasts to acetic, propanoic and benzoic acids and to methyl paraben and pH.
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Mechanism of action of benzoic acid on Zygosaccharomyces bailii: effects on glycolytic metabolite levels, energy production, and intracellular pH.苯甲酸对拜耳接合酵母的作用机制：对糖酵解代谢物水平、能量产生和细胞内pH的影响。
Appl Environ Microbiol. 1991 Dec;57(12):3410-4. doi: 10.1128/aem.57.12.3410-3414.1991.
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Physiological effects of seven different blocks in glycolysis in Saccharomyces cerevisiae.酿酒酵母中糖酵解的七种不同阻断的生理效应。
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苯甲酸对酿酒酵母糖酵解代谢物水平及细胞内pH的影响。

Effect of benzoic acid on glycolytic metabolite levels and intracellular pH in Saccharomyces cerevisiae.

作者信息

Warth A D

机构信息

Division of Food Processing, Commonwealth Scientific and Industrial Research Organization, North Ryde, New South Wales, Australia.

出版信息

Appl Environ Microbiol. 1991 Dec;57(12):3415-7. doi: 10.1128/aem.57.12.3415-3417.1991.

DOI:10.1128/aem.57.12.3415-3417.1991
PMID:1785917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC183989/
Abstract

Low concentrations of benzoic acid stimulated fermentation rates in Saccharomyces cerevisiae. At concentrations near the maximum permitting growth, there was inhibition of fermentation, lowered ATP and intracellular pH, and relatively greater accumulation of benzoate. Changes in the levels of glycolytic intermediates suggested that fermentation was inhibited as a result of high ATP usage rather than of lowered intracellular pH. Specific inhibition of phosphofructokinase or of several other glycolytic enzymes was not observed.

摘要

低浓度的苯甲酸刺激了酿酒酵母的发酵速率。在接近最大允许生长浓度时，发酵受到抑制，ATP和细胞内pH值降低，苯甲酸积累相对更多。糖酵解中间产物水平的变化表明，发酵受到抑制是由于ATP消耗量大，而非细胞内pH值降低。未观察到磷酸果糖激酶或其他几种糖酵解酶的特异性抑制作用。