Bull World Health Organ. 1991;69(6):767-77.
The WHO Multinational Project for Childhood Diabetes, known as the DIAMOND Project, has been responsible for establishing insulin-dependent diabetes mellitus (IDDM) registries and for carrying out diabetes incidence studies, descriptive epidemiological research, and analytical investigations which are being used to test specific hypotheses regarding the etiology of the disease. Standardized epidemiological data are being collected from countries around the world, permitting international comparisons between registries. Multinational studies are also beginning to investigate the potential genetic determinants of the disease, and are contributing to the development of familial IDDM epidemiology worldwide. The development of standards for data collection of IDDM family histories is important for multinational studies of IDDM recurrence risks in families, descriptive analyses of patterns of familial aggregation, and comparative analytical investigations of specific etiological determinants of IDDM in relatives. These activities are being implemented through the DIAMOND Project.
世界卫生组织的儿童糖尿病多国项目，即“钻石项目”，负责建立胰岛素依赖型糖尿病（IDDM）登记处，并开展糖尿病发病率研究、描述性流行病学研究以及分析性调查，这些研究用于检验有关该疾病病因的特定假设。正在从世界各国收集标准化的流行病学数据，以便对各登记处进行国际比较。多国研究也开始调查该疾病潜在的遗传决定因素，并为全球家族性IDDM流行病学的发展做出贡献。制定IDDM家族病史数据收集标准对于IDDM家族复发风险的多国研究、家族聚集模式的描述性分析以及IDDM亲属中特定病因决定因素的比较分析调查而言至关重要。这些活动正在通过“钻石项目”实施。
