Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors.
作者信息
Vegas Arturo J, Bradner James E, Tang Weiping, McPherson Olivia M, Greenberg Edward F, Koehler Angela N, Schreiber Stuart L
机构信息
Howard Hughes Medical Institute, Chemistry and Chemical Biology, Harvard University, Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, MA 02142, USA.
出版信息
Angew Chem Int Ed Engl. 2007;46(42):7960-4. doi: 10.1002/anie.200703198.
Abstract
摘要
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本文引用的文献
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J Cell Sci. 2007 Apr 15;120(Pt 8):1469-79. doi: 10.1242/jcs.03431. Epub 2007 Mar 27.
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Fluorous-enhanced multicomponent reactions for making drug-like library scaffolds.用于制备类药库支架的氟增强多组分反应。
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Chromatin modifications and their function.染色质修饰及其功能。
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The epigenomics of cancer.癌症的表观基因组学。
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The mammalian epigenome.哺乳动物表观基因组。
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