Suppr超能文献

[二乙烟酰胺(可拉明)对四氯化碳中毒家兔肝脏羟化功能的稳定作用]

[Diethylnicotinamid (cordiamine) stabilization of the liver hydroxylating function in rabbits with CCl4 poisoning].

作者信息

Zavodnik L B, Bushma M I, Lukienko P I, Abakumov G Z, Zverinskiĭ I V, Tsyrkunov V M

出版信息

Farmakol Toksikol. 1991 Jul-Aug;54(4):69-71.

PMID:1786835
Abstract

Three and ten days after the administration of CCl4 (subcutaneously, once, 4 ml/kg of 50% oil solution) there were found a decrease of the rate of antipyrine elimination (intravenously, 50 mg/kg) from the blood plasma, an increase of the total bilirubin content, ALT activity and stimulation of lipid peroxidation processes. Cordiamine administration (subcutaneously, twice a day, 3 and 10 days) exerts the normalizing effect.

摘要

在皮下注射四氯化碳(50%油溶液,4 ml/kg,单次)后的第3天和第10天,发现血浆中安替比林清除率(静脉注射,50 mg/kg)降低,总胆红素含量、谷丙转氨酶活性升高,脂质过氧化过程受到刺激。注射可拉明(皮下注射,每天两次,共3天和10天)具有归一化作用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验