Zavodnik L B, Bushma M I, Lukienko P I, Abakumov G Z, Zverinskiĭ I V, Tsyrkunov V M
Farmakol Toksikol. 1991 Jul-Aug;54(4):69-71.
Three and ten days after the administration of CCl4 (subcutaneously, once, 4 ml/kg of 50% oil solution) there were found a decrease of the rate of antipyrine elimination (intravenously, 50 mg/kg) from the blood plasma, an increase of the total bilirubin content, ALT activity and stimulation of lipid peroxidation processes. Cordiamine administration (subcutaneously, twice a day, 3 and 10 days) exerts the normalizing effect.
在皮下注射四氯化碳(50%油溶液,4 ml/kg,单次)后的第3天和第10天,发现血浆中安替比林清除率(静脉注射,50 mg/kg)降低,总胆红素含量、谷丙转氨酶活性升高,脂质过氧化过程受到刺激。注射可拉明(皮下注射,每天两次,共3天和10天)具有归一化作用。