Karoussis Ioannis K, Kotsovilis Sotirios, Fourmousis Ioannis
Department of Periodontology, School of Dental Medicine, University of Athens, Athens, Greece.
Clin Oral Implants Res. 2007 Dec;18(6):669-79. doi: 10.1111/j.1600-0501.2007.01406.x. Epub 2007 Sep 13.
The outcome of implant treatment in periodontally compromised partially edentulous patients has not been completely clarified. Therefore, the aim of the present study was to perform, applying a systematic methodology, a comprehensive and critical review of the prospective studies published in English up to and including August 2006, regarding the short-term (<5 years) and long-term (>or=5 years) prognosis of osseointegrated implants placed in periodontally compromised partially edentulous patients.
Using The National Library Of Medicine and Cochrane Oral Health Group databases, a literature search for articles published up to and including August 2006 was performed. At the first phase of selection the titles and abstracts and at the second phase full papers were screened independently and in duplicate by the three reviewers (I. K. K., S. K., I. F.).
The search provided 2987 potentially relevant titles and abstracts. At the first phase of evaluation, 2956 publications were rejected based on title and abstract. At the second phase, the full text of the remaining 31 publications was retrieved for more detailed evaluation. Finally, 15 prospective studies were selected, including seven short-term and eight long-term studies. Because of considerable discrepancies among these studies, meta-analysis was not performed.
No statistically significant differences in both short-term and long-term implant survival exist between patients with a history of chronic periodontitis and periodontally healthy individuals. Patients with a history of chronic periodontitis may exhibit significantly greater long-term probing pocket depth, peri-implant marginal bone loss and incidence of peri-implantitis compared with periodontally healthy subjects. Even though the short-term implant prognosis for patients treated for aggressive periodontitis is acceptable, on a long-term basis the matter is open to question. Alterations in clinical parameters around implants and teeth in aggressive periodontitis patients may not follow the same pattern, in contrast to what has been reported for chronic periodontitis patients. However, as only three studies comprising patients treated for aggressive periodontitis were selected, more studies, specially designed, are required to evaluate implant prognosis in this subtype of periodontitis. As the selected publications exhibited considerable discrepancies, more studies, uniformly designed, preferably longitudinal, prospective and controlled, would be important.
牙周状况不佳的部分牙列缺损患者种植治疗的结果尚未完全明确。因此，本研究的目的是运用系统方法，对截至2006年8月（含8月）以英文发表的前瞻性研究进行全面且批判性的综述，内容涉及牙周状况不佳的部分牙列缺损患者植入骨整合种植体的短期（<5年）和长期（≥5年）预后。
利用美国国立医学图书馆和考克兰口腔健康组数据库，检索截至2006年8月（含8月）发表的文章。在筛选的第一阶段，由三位评审员（I.K.K.、S.K.、I.F.）独立且重复地筛选标题和摘要；在第二阶段，筛选全文。
检索得到2987个潜在相关的标题和摘要。在评估的第一阶段，基于标题和摘要排除了2956篇出版物。在第二阶段，检索了其余31篇出版物的全文以进行更详细的评估。最终，选择了15项前瞻性研究，包括7项短期研究和8项长期研究。由于这些研究之间存在相当大的差异，未进行荟萃分析。
有慢性牙周炎病史的患者与牙周健康个体在种植体短期和长期存留率方面均无统计学上的显著差异。与牙周健康受试者相比，有慢性牙周炎病史的患者可能表现出显著更深的长期探诊深度、种植体周围边缘骨吸收以及种植体周炎的发生率。尽管侵袭性牙周炎患者种植体的短期预后尚可，但从长期来看仍存在疑问。与慢性牙周炎患者的报道相反，侵袭性牙周炎患者种植体和牙齿周围临床参数的变化可能不遵循相同模式。然而，由于仅选择了三项包含侵袭性牙周炎患者治疗情况的研究，因此需要更多专门设计的研究来评估这种牙周炎亚型患者的种植预后。由于所选出版物存在相当大的差异，更多统一设计的研究，最好是纵向、前瞻性且对照的研究，将具有重要意义。
