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双相情感障碍中神经认知障碍与功能障碍之间的关系:一项初步研究。

A relationship between neurocognitive impairment and functional impairment in bipolar disorder: a pilot study.

作者信息

Altshuler Lori L, Bearden Carrie E, Green Michael F, van Gorp Wilfred, Mintz Jim

机构信息

Department of Psychiatry, VA Greater Los Angeles Healthcare System, West Los Angeles Medical Center, Los Angeles, CA, USA.

出版信息

Psychiatry Res. 2008 Jan 15;157(1-3):289-93. doi: 10.1016/j.psychres.2007.01.001. Epub 2007 Sep 14.

DOI:10.1016/j.psychres.2007.01.001
PMID:17868903
Abstract

We assessed the relationship between neurocognitive status and role function in 14 euthymic bipolar subjects. Role function scores were bimodally distributed. Poor verbal memory and executive function were associated with functional impairment, suggesting that functional disability may be restricted to a subgroup of cognitively impaired bipolar patients.

摘要

我们评估了14名心境正常的双相情感障碍患者的神经认知状态与角色功能之间的关系。角色功能得分呈双峰分布。言语记忆和执行功能较差与功能损害相关,这表明功能残疾可能仅限于认知受损的双相情感障碍患者亚组。

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