Akimkina Tatiana, Venien-Bryan Catherine, Hodgkin Jonathan
Genetics Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.
Res Microbiol. 2007 Sep;158(7):582-90. doi: 10.1016/j.resmic.2007.06.005. Epub 2007 Jul 13.
We report the discovery, properties and complete sequence (46,365bp) of Min1, the first bacteriophage to be reported for the coryneform genus Microbacterium. This temperate phage is normally integrated into a stable plasmid, pMN1, found in cells of Microbacterium nematophilum, a pathogen of certain soil nematodes including Caenorhabditis elegans, but it can also grow lytically. The phage is lambdoid in morphology and in sequence, belonging to the family Siphoviridae. General and specific features of the genome are discussed, together with possible contributions of the phage to host virulence.
我们报告了Min1噬菌体的发现、特性及完整序列（46,365bp），它是棒状杆菌属微小杆菌中首个被报道的噬菌体。这种温和噬菌体通常整合到一种稳定的质粒pMN1中，该质粒存在于嗜线虫微小杆菌的细胞中，嗜线虫微小杆菌是包括秀丽隐杆线虫在内的某些土壤线虫的病原体，但它也能进行裂解生长。该噬菌体在形态和序列上属于λ样噬菌体，属于长尾噬菌体科。本文讨论了基因组的一般和特定特征，以及该噬菌体对宿主毒力可能产生的影响。
