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印度北部人类免疫缺陷病毒患者中乙型肝炎病毒和丙型肝炎病毒合并感染的低患病率。

Low prevalence of hepatitis B virus and hepatitis C virus co-infection in patients with human immunodeficiency virus in Northern India.

作者信息

Tripathi A K, Khanna M, Gupta N, Chandra M

机构信息

AIDS Care and ART Center, King George's Medical University, Lucknow, India.

出版信息

J Assoc Physicians India. 2007 Jun;55:429-31.

Abstract

AIM

To study the prevalence of HBV and HCV co-infection in patients with HIV attending a referral hospital in Northern India.

METHODS AND MATERIAL

The study cohort included six hundred and twenty consecutive HIV infected patients who were studied for co-infection with HBV/HCV or both. It included four hundred and seventy two male and one hundred and forty eight female patients between the age group 25-50 years. HBV and HCV infection was diagnosed by ELISA. Other routine investigations were also done.

RESULTS

Out of a total of 620 consecutive HIV infected patients studied, HBV co-infection was detected in 14/ 620 (2.25%) patients and HCV co-infection in 10/620 (1.61%) patients and dual co-infection (HBV/HCV) in 1/620(0.16%). The mode of transmission of HBV was sexual contact in all (100%), while for HCV it was sexual contact in 5 patients (50%), blood transfusion in 4 patients (40%) and intravenous drug use (IDU) in 1 patient (10%).

CONCLUSION

The prevalence of co-infection with HBV/HCV is much lower in our study population as compared to that reported in Western literature.

摘要

目的

研究印度北部一家转诊医院中感染人类免疫缺陷病毒(HIV)患者的乙肝病毒(HBV)和丙肝病毒(HCV)合并感染率。

方法与材料

研究队列包括620例连续的HIV感染患者,对其进行HBV/HCV或两者合并感染情况的研究。其中包括472例男性和148例女性患者,年龄在25至50岁之间。通过酶联免疫吸附测定(ELISA)诊断HBV和HCV感染。还进行了其他常规检查。

结果

在总共620例连续研究的HIV感染患者中,检测到14/620(2.25%)例患者合并HBV感染,10/620(1.61%)例患者合并HCV感染,1/620(0.16%)例患者合并HBV/HCV双重感染。HBV的传播方式均为性接触(100%),而HCV的传播方式为:5例患者(50%)为性接触,4例患者(40%)为输血,1例患者(10%)为静脉吸毒(IDU)。

结论

与西方文献报道相比,我们研究人群中HBV/HCV合并感染率要低得多。

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