Tripathi A K, Khanna M, Gupta N, Chandra M
AIDS Care and ART Center, King George's Medical University, Lucknow, India.
J Assoc Physicians India. 2007 Jun;55:429-31.
To study the prevalence of HBV and HCV co-infection in patients with HIV attending a referral hospital in Northern India.
The study cohort included six hundred and twenty consecutive HIV infected patients who were studied for co-infection with HBV/HCV or both. It included four hundred and seventy two male and one hundred and forty eight female patients between the age group 25-50 years. HBV and HCV infection was diagnosed by ELISA. Other routine investigations were also done.
Out of a total of 620 consecutive HIV infected patients studied, HBV co-infection was detected in 14/ 620 (2.25%) patients and HCV co-infection in 10/620 (1.61%) patients and dual co-infection (HBV/HCV) in 1/620(0.16%). The mode of transmission of HBV was sexual contact in all (100%), while for HCV it was sexual contact in 5 patients (50%), blood transfusion in 4 patients (40%) and intravenous drug use (IDU) in 1 patient (10%).
The prevalence of co-infection with HBV/HCV is much lower in our study population as compared to that reported in Western literature.
研究印度北部一家转诊医院中感染人类免疫缺陷病毒（HIV）患者的乙肝病毒（HBV）和丙肝病毒（HCV）合并感染率。
研究队列包括620例连续的HIV感染患者，对其进行HBV/HCV或两者合并感染情况的研究。其中包括472例男性和148例女性患者，年龄在25至50岁之间。通过酶联免疫吸附测定（ELISA）诊断HBV和HCV感染。还进行了其他常规检查。
在总共620例连续研究的HIV感染患者中，检测到14/620（2.25%）例患者合并HBV感染，10/620（1.61%）例患者合并HCV感染，1/620（0.16%）例患者合并HBV/HCV双重感染。HBV的传播方式均为性接触（100%），而HCV的传播方式为：5例患者（50%）为性接触，4例患者（40%）为输血，1例患者（10%）为静脉吸毒（IDU）。
与西方文献报道相比，我们研究人群中HBV/HCV合并感染率要低得多。
