von Bierbrauer A, Mennel H D, Leyhe A, von Wichert P
Philipps-Universität Marburg.
Vasa Suppl. 1991;33:262-3.
In cases of suspected microangiopathies morphologic abnormal capillaries were identified and marked by nailfold capillary microscopy (NCM). The marked nailfold areas were precisely biopsied and the biopsies were examined by electronic-microscopy and light microscopy (HE and immune-histochemical). Histological findings well correlated with clinical and capillaroscopical findings. It is concluded that NCM-assisted nailfold biopsy helps to achieve histologic proof of microangiopathies and improves diagnostic accuracy in collagen vascular diseases and vasculitides.
在疑似微血管病变的病例中，通过甲襞毛细血管显微镜检查（NCM）识别并标记形态异常的毛细血管。对标记的甲襞区域进行精确活检，并通过电子显微镜和光学显微镜（苏木精-伊红染色和免疫组织化学染色）对活检组织进行检查。组织学结果与临床和毛细血管镜检查结果密切相关。结论是，NCM辅助的甲襞活检有助于获得微血管病变的组织学证据，并提高胶原血管疾病和血管炎的诊断准确性。
