Barutzki S, Heidrich H, Alten R, Sörensen H, von Werder K
Innere Abteilung Franziskus-Krankenhaus, Berlin.
Vasa Suppl. 1991;33:259-60.
Microangiopathic changes in capillary architecture associated with collagen diseases can be visualized by vital capillary microscopy. In our study of 100 patients with collagen disease we found typical capillaroscopic images in 64%. Differentiation in subclasses showed the highest diagnostic value of this method in systemic sclerosis (77%) and rheumatoid arthritis (68%). It was lower in patients with Sharp- and CREST-syndrome (55%) and very low in systemic lupus erythematosus (33%). In summary, vital capillary microscopy is a valid method in non-invasive diagnostic of collagen diseases.
与胶原病相关的毛细血管结构微血管病变可通过活体毛细血管显微镜观察到。在我们对100例胶原病患者的研究中，64%的患者发现了典型的毛细血管镜图像。亚类分化显示该方法在系统性硬化症（77%）和类风湿性关节炎（68%）中具有最高的诊断价值。在夏普综合征和CREST综合征患者中该值较低（55%），在系统性红斑狼疮患者中非常低（33%）。总之，活体毛细血管显微镜检查是胶原病无创诊断的有效方法。
