Schloemer R H, Schlom J, Schochetman G, Kimball P, Wagner R R
J Virol. 1976 May;18(2):804-8. doi: 10.1128/JVI.18.2.804-808.1976.
Neuraminidase treatment of mouse mammary tumor virus, Rauscher murine leukemia virus, and Mason-Pfizer monkey virus resulted in loss of their capacity to inhibit hemagglutination of influenza virus. Hemagglutination-inhibition activity of these RNA tumor viruses could be restored by in vitro resialylation catalyzed by sialyl transferase. The major glycoprotein in the intact envelope of desialylated and, to some extent, native virions could be specificallly labeled in vitro with CMP-(14C) sialic acid. These studies further characterize the individual glycoproteins of mouse mammary tumor virus, Rauscher murine leukemia virus, and Mason-Pfizer monkey virus.
用神经氨酸酶处理小鼠乳腺肿瘤病毒、劳舍尔小鼠白血病病毒和梅森- Pfizer猴病毒，导致它们抑制流感病毒血凝的能力丧失。这些RNA肿瘤病毒的血凝抑制活性可通过唾液酸转移酶催化的体外再唾液酸化来恢复。去唾液酸化的完整包膜以及在一定程度上天然病毒粒子中的主要糖蛋白，可在体外被CMP -（14C）唾液酸特异性标记。这些研究进一步表征了小鼠乳腺肿瘤病毒、劳舍尔小鼠白血病病毒和梅森- Pfizer猴病毒各自的糖蛋白。
