Zamoyska Rose
Medical Research Council National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA UK.
Immunity. 2007 Sep;27(3):421-3. doi: 10.1016/j.immuni.2007.08.009.
The balance between kinases and phosphatases is crucial for regulating lymphocyte signaling. In this issue, McNeill et al. (2007) show that the transmembrane phosphatase CD45 has a role as both positive and negative regulator of T cell signaling.
激酶和磷酸酶之间的平衡对于调节淋巴细胞信号传导至关重要。在本期中，麦克尼尔等人（2007年）表明跨膜磷酸酶CD45在T细胞信号传导中既是正调节因子又是负调节因子。
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