First International Meeting on Quadruplex DNA.
作者信息
Wilson W David, Sugiyama Hiroshi
机构信息
Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA.
出版信息
ACS Chem Biol. 2007 Sep 21;2(9):589-94. doi: 10.1021/cb7001686.
Abstract
摘要
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First International Meeting on Quadruplex DNA.第一届四链体DNA国际会议。
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G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase.端粒 DNA 3' 末端的 G-四链体形成抑制端粒酶、聚合酶的延伸和解旋酶的解旋。
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I-motif and quadruplex-based device that can control a protein release or bind and release small molecule to influence biological processes.基于I-基序和四链体的装置，可控制蛋白质释放或结合并释放小分子以影响生物过程。
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Telomerase recruitment by the telomere end binding protein-beta facilitates G-quadruplex DNA unfolding in ciliates.端粒末端结合蛋白β招募端粒酶促进纤毛虫中G-四链体DNA解折叠。
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本文引用的文献
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The tetraplex (CGG)n destabilizing proteins hnRNP A2 and CBF-A enhance the in vivo translation of fragile X premutation mRNA.四链体（CGG）n去稳定蛋白hnRNP A2和CBF-A增强了脆性X前突变mRNA的体内翻译。
Nucleic Acids Res. 2007;35(17):5775-88. doi: 10.1093/nar/gkm636. Epub 2007 Aug 23.
2
Mechanism of acridine-based telomerase inhibition and telomere shortening.基于吖啶的端粒酶抑制和端粒缩短机制。
Biochem Pharmacol. 2007 Sep 1;74(5):679-89. doi: 10.1016/j.bcp.2007.06.011. Epub 2007 Jun 16.
3
Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence.K⁺溶液中 Hybrid-2 型分子内人端粒 G-四链体的结构：对人端粒序列结构多态性的见解
Nucleic Acids Res. 2007;35(15):4927-40. doi: 10.1093/nar/gkm522. Epub 2007 Jul 10.
4
Structure of a human telomeric DNA sequence stabilized by 8-bromoguanosine substitutions, as determined by NMR in a K+ solution.在钾离子溶液中通过核磁共振确定的由8-溴鸟苷取代稳定的人类端粒DNA序列结构。
FEBS J. 2007 Jul;274(14):3545-3556. doi: 10.1111/j.1742-4658.2007.05881.x. Epub 2007 Jun 11.
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Human telomere quadruplex: refolding and selection of individual conformers via RNA/DNA chimeric editing.人类端粒四链体：通过RNA/DNA嵌合编辑对单个构象异构体进行重折叠和筛选
Biochemistry. 2007 Jun 26;46(25):7599-606. doi: 10.1021/bi602392u. Epub 2007 Jun 1.
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Guanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes.鸟嘌呤是四联体的最佳“伙伴”：碱基替换对四分子四链体动力学和稳定性的影响
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Artificial G-wire switch with 2,2'-bipyridine units responsive to divalent metal ions.具有对二价金属离子有响应的2,2'-联吡啶单元的人工G-线开关。
J Am Chem Soc. 2007 May 9;129(18):5919-25. doi: 10.1021/ja068707u. Epub 2007 Apr 18.
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Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation.钾溶液中分子内人端粒G-四链体的结构：一种新型腺嘌呤三联体的形成
Nucleic Acids Res. 2007;35(7):2440-50. doi: 10.1093/nar/gkm009. Epub 2007 Mar 29.
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Quadruplex ligands may act as molecular chaperones for tetramolecular quadruplex formation.四链体配体可能作为分子伴侣促进四分子四链体的形成。
Nucleic Acids Res. 2007;35(8):2483-93. doi: 10.1093/nar/gkm098. Epub 2007 Mar 29.
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G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas.富含鸟嘌呤的原癌基因是B细胞淋巴瘤基因组不稳定的靶点。
Cancer Res. 2007 Mar 15;67(6):2586-94. doi: 10.1158/0008-5472.CAN-06-2419.
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