Storozhenko Sergei, De Brouwer Veerle, Volckaert Maarten, Navarrete Oscar, Blancquaert Dieter, Zhang Guo-Fang, Lambert Willy, Van Der Straeten Dominique
Unit Plant Hormone Signalling and Bio-imaging, Department of Molecular Genetics, Ghent University, K.L. Ledeganckstraat 35, B-9000 Ghent, Belgium.
Nat Biotechnol. 2007 Nov;25(11):1277-9. doi: 10.1038/nbt1351. Epub 2007 Oct 14.
Rice, the world's major staple crop, is a poor source of essential micronutrients, including folates (vitamin B9). We report folate biofortification of rice seeds achieved by overexpressing two Arabidopsis thaliana genes of the pterin and para-aminobenzoate branches of the folate biosynthetic pathway from a single locus. We obtained a maximal enhancement as high as 100 times above wild type, with 100 g of polished raw grains containing up to four times the adult daily folate requirement.
水稻是世界主要主食作物，但却是必需微量营养素（包括叶酸（维生素B9））的不良来源。我们报告了通过从单个位点过表达拟南芥叶酸生物合成途径中蝶呤和对氨基苯甲酸分支的两个基因实现水稻种子叶酸生物强化。我们获得了高达野生型100倍的最大增强效果，100克糙米粉含有的叶酸高达成年人每日需求量的四倍。
