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小型非编码RNA、哺乳动物细胞与病毒:调控相互作用?

Small non-coding RNAs, mammalian cells, and viruses: regulatory interactions?

作者信息

Yeung Man Lung, Benkirane Monsef, Jeang Kuan-Teh

机构信息

Molecular Virology Section, Laboratory of Molecular Microbiology National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, Maryland 20892-0460, USA.

出版信息

Retrovirology. 2007 Oct 15;4:74. doi: 10.1186/1742-4690-4-74.

Abstract

Recent findings suggest that mammalian cells can use small non-coding RNAs (ncRNA) to regulate physiological viral infections. Here, we comment on several lines of evidence that support this concept. We discuss how viruses may in turn protect, suppress, evade, modulate, or adapt to the host cell's ncRNA regulatory schema.

摘要

最近的研究结果表明,哺乳动物细胞可以利用小的非编码RNA(ncRNA)来调节生理性病毒感染。在此,我们对支持这一概念的几条证据进行评论。我们讨论了病毒如何反过来保护、抑制、逃避、调节或适应宿主细胞的ncRNA调控模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/080f/2164956/02e46462c708/1742-4690-4-74-1.jpg

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