Bray Freddie, Wibe Arne, Dørum Liv Marit R, Møller Bjørn
Institutt for populasjonsbasert kreftforskning, Kreftregisteret, 0310 Oslo.
Tidsskr Nor Laegeforen. 2007 Oct 18;127(20):2682-7.
The incidence of colorectal cancer has increased rapidly in both sexes during the last 50 years, and the disease is today the most frequent form of cancer diagnosed in Norway. This paper provides an overview of the incidence, mortality and survival of colorectal cancer in Norway; it discusses known and assumed causality and the prospects for prevention, screening and treatment.
Colorectal cancers diagnosed in Norway were obtained from the Cancer Registry of Norway by location (colon and rectum) and 5-year age group for each year in the period 1953-2005. Data obtained from the NORDCAN, GLOBOCAN and EUROCARE databases were used to compare incidence, mortality and survival in Norway with corresponding data from the Nordic and European countries.
Age-adjusted rates have doubled since the 1960s. Norway used to have a lower risk of colorectal cancer than its Northern European neighbours, but now has the highest rate in the Nordic countries and one of the highest in Europe.
The rates for colorectal cancer appear to be stabilising, especially among the younger generations.
在过去50年中，结直肠癌的发病率在男女两性中均迅速上升，如今该疾病是挪威诊断出的最常见癌症形式。本文概述了挪威结直肠癌的发病率、死亡率和生存率；讨论了已知和假定的因果关系以及预防、筛查和治疗的前景。
从挪威癌症登记处获取1953年至2005年期间每年按部位（结肠和直肠）及5岁年龄组划分的挪威诊断出的结直肠癌病例。从NORDCAN、GLOBOCAN和EUROCARE数据库获取的数据用于比较挪威的发病率、死亡率和生存率与北欧及欧洲国家的相应数据。
自20世纪60年代以来，年龄调整率翻了一番。挪威过去患结直肠癌的风险低于其北欧邻国，但现在是北欧国家中发病率最高的，也是欧洲发病率最高的国家之一。
结直肠癌的发病率似乎趋于稳定，尤其是在年轻一代中。
