Lee F, Lin Y-J, Deng M-C, Lee T-Y, Huang C-C
Animal Health Research Institute, Tamsui, Taipei County, Taiwan.
J Med Primatol. 2007 Dec;36(6):343-7. doi: 10.1111/j.1600-0684.2007.00211.x.
A total of 284 non-human primate sera were collected between December 2004 and September 2005 and tested by a commercially available dot immunobinding assay for the antibodies to cercopithecine herpesvirus 1, an alphaherpesvirus with high mortality for infected humans.
Seropositive rates were 58% among non-human primates from animal shelters and 38% among those from zoos and academic institutes. Positive reactors were found in three species, the Formosan macaque (Macaca cyclopis; 57%), the cynomolgus macaque (Macaca fascicularis; 11%) and the olive baboon (Papio anubis; 68%).
Our results showed that natural infection by cercopithecine herpesvirus 1 in Formosan macaques was highly prevalent, and to a certain extent reflected the situation of the wild populations in Taiwan. The findings raised the issues of zoonotic public health and the occupational health of primate workers. High positive rate in olive baboons was also found, although, it cannot be ruled out that the positivity was due to cross-reactivity between cercopithecine herpesvirus 1 and other herpesviruses.
2004年12月至2005年9月期间共收集了284份非人灵长类动物血清，并采用市售斑点免疫结合试验检测了针对猕猴疱疹病毒1型的抗体，该病毒是一种对人类感染具有高致死率的α疱疹病毒。
动物收容所的非人灵长类动物血清阳性率为58%，动物园和学术机构的为38%。在三个物种中发现了阳性反应动物，即台湾猕猴（食蟹猴；57%）、食蟹猕猴（猕猴；11%）和东非狒狒（草原狒狒；68%）。
我们的结果表明，台湾猕猴感染猕猴疱疹病毒1型的自然感染率很高，在一定程度上反映了台湾野生种群的情况。这些发现引发了人畜共患公共卫生问题以及灵长类动物工作人员的职业健康问题。虽然不能排除东非狒狒的阳性反应是由于猕猴疱疹病毒1型与其他疱疹病毒之间的交叉反应，但在东非狒狒中也发现了高阳性率。
