Nishimura Jun, Arai Norimitsu, Tohmatsu Jun-ichi
Sanko Junyaku Co., Ltd, Department of Research and Development.
Clin Calcium. 2007 Nov;17(11):1702-8.
We evaluated the effectiveness of the "Picolumi ucOC" kit for measuring the serum level of ucOC. When used with an autoanalyzer, the kit achieved highly sensitive and rapid measurement over a range of 0.39 to 50 ng/mL. Assessment of reproducibility testing showed good results, since the coefficient of variation was <or= 10%, the recovery rate for spiked samples was 93 - 106%, and there was no influence of interfering substances at normal levels. Among healthy individuals, serum ucOC levels were shown to be high in teenagers, who have very active bone metabolism, and in women aged 45 years or older, whose bone metabolism is influenced by menopause.
我们评估了“Picolumi ucOC”试剂盒用于测量血清中ucOC水平的有效性。当与自动分析仪一起使用时，该试剂盒在0.39至50 ng/mL的范围内实现了高灵敏度和快速测量。重复性测试评估显示结果良好，因为变异系数≤10%，加标样品的回收率为93 - 106%，并且正常水平的干扰物质没有影响。在健康个体中，血清ucOC水平在青少年中较高，他们的骨代谢非常活跃，在45岁及以上的女性中也较高，她们的骨代谢受更年期影响。
