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转基因植物的毒性研究:已发表文献综述

Toxicity studies of genetically modified plants: a review of the published literature.

作者信息

Domingo José L

机构信息

Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira I Virgili University, San Lorenzo, Reus, Spain.

出版信息

Crit Rev Food Sci Nutr. 2007;47(8):721-33. doi: 10.1080/10408390601177670.

DOI:10.1080/10408390601177670
PMID:17987446
Abstract

According to the information reported by the WHO, the genetically modified (GM) products that are currently on the international market have all passed risk assessments conducted by national authorities. These assessments have not indicated any risk to human health. In spite of this clear statement, it is quite amazing to note that the review articles published in international scientific journals during the current decade did not find, or the number was particularly small, references concerning human and animal toxicological/health risks studies on GM foods. In this paper, the scientific information concerning the potential toxicity of GM/transgenic plants using the Medline database is reviewed. Studies about the safety of the potential use of potatoes, corn, soybeans, rice, cucumber, tomatoes, sweet pepper, peas, and canola plants for food and feed were included. The number of references was surprisingly limited. Moreover, most published studies were not performed by the biotechnology companies that produce these products. This review can be concluded raising the following question: where is the scientific evidence showing that GM plants/food are toxicologically safe?

摘要

根据世界卫生组织报告的信息,目前国际市场上的转基因产品均已通过国家当局进行的风险评估。这些评估并未表明对人类健康有任何风险。尽管有这一明确声明,但值得注意的是,在当前十年间国际科学期刊上发表的综述文章中,关于转基因食品对人类和动物毒理学/健康风险研究的参考文献要么未被找到,要么数量特别少,这相当令人惊讶。在本文中,我们利用医学在线数据库(Medline)对有关转基因/转基因植物潜在毒性的科学信息进行了综述。其中包括了关于将土豆、玉米、大豆、水稻、黄瓜、西红柿、甜椒、豌豆和油菜植物用于食品和饲料的潜在安全性研究。参考文献的数量惊人地有限。此外,大多数已发表的研究并非由生产这些产品的生物技术公司进行。本综述可以通过提出以下问题来结束:表明转基因植物/食品在毒理学上安全的科学证据在哪里?

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引用本文的文献

1
Safety Assessment of Genetically Modified Feed: Is There Any Difference From Food?转基因饲料的安全性评估:它与食品有何不同?
Front Plant Sci. 2019 Dec 11;10:1592. doi: 10.3389/fpls.2019.01592. eCollection 2019.
2
Debate on GMOs health risks after statistical findings in regulatory tests.在监管测试中的统计发现之后,关于转基因生物健康风险的争论。
Int J Biol Sci. 2010 Oct 5;6(6):590-8. doi: 10.7150/ijbs.6.590.
3
Demographic responses of Daphnia magna fed transgenic Bt-maize.饲喂转 Bt 玉米的大型溞的种群响应。
Ecotoxicology. 2010 Feb;19(2):419-30. doi: 10.1007/s10646-009-0427-x. Epub 2009 Oct 27.
4
Under wraps.
Nat Biotechnol. 2009 Oct;27(10):880-2. doi: 10.1038/nbt1009-880.
5
How subchronic and chronic health effects can be neglected for GMOs, pesticides or chemicals.转基因生物、农药或化学品的亚慢性和慢性健康影响怎么能被忽视呢。
Int J Biol Sci. 2009 Jun 17;5(5):438-43. doi: 10.7150/ijbs.5.438.
6
Errors in text.文本中的错误。
J R Soc Med. 2008 Sep;101(9):435. doi: 10.1258/jrsm.2008.08k016.