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外科重症监护病房入院前的生活质量。

Quality of life before surgical ICU admission.

作者信息

Abelha Fernando J, Santos Cristina C, Barros Henrique

机构信息

Department of Anesthesia and Intensive Care, Hospital de São João, Porto, Portugal.

出版信息

BMC Surg. 2007 Nov 12;7:23. doi: 10.1186/1471-2482-7-23.

Abstract

BACKGROUND

Examining the quality of life (QOL) of patients before ICU admission will allow outcome variables to be compared and analyzed in relation to it. The objective of this study was to analyze QOL of patients before admission to a surgical ICU and to study its relationship to outcome and to the baseline characteristics of the patients.

METHODS

All adult patients consecutively admitted to the surgical ICU between November 2004 and April 2005, who underwent non-cardiac surgery, were enrolled in this observational and prospective study. The following patient characteristics were recorded: age, gender, body mass index, ASA physical status, type and magnitude of surgical procedure, length of stay (LOS), in ICU and in hospital, mortality, Simplified Acute Physiology Score II (SAPS), history of co-morbidities and quality of life survey score (QOLSS). The relationships between QOLSS and ICU variables and outcome were evaluated. The relationship between the total QOLSS and each variable or outcome was assessed by multiple linear regression.

RESULTS

One hundred eighty seven patients completed the study. The preadmission QOLSS of the patients studied was 4.43 +/- 4.90; 28% of patients had a normal quality of life (0 points), 38% had between 1 and 5 points (considered mild deterioration), 21% had between 6 and 10 points (moderate deterioration), 10% had between 11 and 15 points (considered major deterioration) and 3% had more than 15 points (severe limitation of quality of life). A worse preadmission QOLSS was associated with higher SAPS II scores, with older patients (age> 65 years) and with ASA physical status (ASA III/IV). Total QOLSS was significantly worse in elderly patients and in patients with co-morbidities and in patients more severely ill at ICU admission. Patients who died in the ICU and in hospital had worse QOLSS scores compared to those who survived. However, no statistical differences in QOLSS were found in relation to longer ICU stays (ICU LOS).

CONCLUSION

Preadmission QOL correlates with age and severity of illness. Patients with co-morbidities and those who died during ICU or hospital stay had worse QOLSS scores.

摘要

背景

在重症监护病房(ICU)收治患者之前检查其生活质量(QOL),将有助于对结果变量进行与之相关的比较和分析。本研究的目的是分析外科ICU收治患者入院前的生活质量,并研究其与结局以及患者基线特征之间的关系。

方法

纳入2004年11月至2005年4月间连续收治到外科ICU且接受非心脏手术的所有成年患者,进行这项观察性前瞻性研究。记录以下患者特征:年龄、性别、体重指数、美国麻醉医师协会(ASA)身体状况分级、手术类型和大小、在ICU和住院的住院时间(LOS)、死亡率、简化急性生理学评分II(SAPS)、合并症病史和生活质量调查评分(QOLSS)。评估QOLSS与ICU变量及结局之间的关系。通过多元线性回归评估总QOLSS与每个变量或结局之间的关系。

结果

187例患者完成了研究。所研究患者的入院前QOLSS为4.43±4.90;28%的患者生活质量正常(0分),38%的患者得分为1至5分(视为轻度恶化),21%的患者得分为6至10分(中度恶化),10%的患者得分为11至15分(视为重度恶化),3%的患者得分超过15分(生活质量严重受限)。入院前较差的QOLSS与较高的SAPS II评分、老年患者(年龄>65岁)以及ASA身体状况分级(ASA III/IV)相关。老年患者以及有合并症的患者和ICU入院时病情更严重的患者,其总QOLSS明显更差。在ICU和医院死亡的患者与存活患者相比,QOLSS评分更差。然而,在ICU住院时间较长(ICU LOS)方面,未发现QOLSS有统计学差异。

结论

入院前生活质量与年龄和疾病严重程度相关。有合并症的患者以及在ICU或住院期间死亡的患者,其QOLSS评分更差。

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