Magnette C, De Saint Hubert M, Swine C, Bouhon S, Jamart J, Dive A, Michaux I
Department of Intensive Care Medicine, CHU Dinant Godinne University Hospital, Université Catholique de Louvain, Yvoir, Belgium -
Minerva Anestesiol. 2015 Jul;81(7):743-51. Epub 2015 Jan 30.
Because the proportion of elderly patients admitted to the intensive care unit (ICU) is increasing, the objective of this study was to test the hypothesis that very elderly patients with better preadmission functional status would have better medium-term survival and functional status after an ICU stay.
In this observational study, 96 patients (68% surgical and 32% medical) aged ≥80 years and admitted to the ICU between May 2008 and June 2009 were recruited. Functional status was assessed using a modified Katz Scale and the Lawton Scale. Primary outcomes were: one-year mortality and its independent predictive factors, one-year functional status and perceived quality of life.
Multivariate analysis showed that type of admission (surgical vs. medical), existence of cancer, Sequential Organ Failure Assessment (SOFA) Score at ICU admission and occurrence of septic complications during the ICU stay were independent predictive factors for one-year mortality, but preadmission functional status was not. At one year, despite functional decline in 50% of survivors, 68% perceived their health status to be equivalent to or better than before and 82.6% would agree to a further ICU stay.
One-year mortality of very elderly patients after an ICU stay is not related to preadmission functional status but to the type of admission, existence of cancer, SOFA Score at ICU admission and occurrence of septic complications during the ICU stay. Despite functional decline in half of these patients, one year after admission 82.6% would agree to another ICU stay.
由于入住重症监护病房(ICU)的老年患者比例不断增加,本研究的目的是检验以下假设:入院前功能状态较好的高龄患者在ICU住院后会有更好的中期生存率和功能状态。
在这项观察性研究中,招募了96例年龄≥80岁、于2008年5月至2009年6月期间入住ICU的患者(68%为外科患者,32%为内科患者)。使用改良的Katz量表和Lawton量表评估功能状态。主要结局包括:一年死亡率及其独立预测因素、一年功能状态和感知生活质量。
多变量分析显示,入院类型(外科与内科)、癌症的存在、ICU入院时的序贯器官衰竭评估(SOFA)评分以及ICU住院期间败血症并发症的发生是一年死亡率的独立预测因素,但入院前功能状态不是。一年时,尽管50%的幸存者功能下降,但68%的人认为他们的健康状况与之前相当或更好,82.6%的人会同意再次入住ICU。
高龄患者ICU住院后的一年死亡率与入院前功能状态无关,而是与入院类型、癌症的存在、ICU入院时的SOFA评分以及ICU住院期间败血症并发症的发生有关。尽管这些患者中有一半功能下降,但入院一年后82.6%的人会同意再次入住ICU。