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NONCODE v2.0:解码非编码信息

NONCODE v2.0: decoding the non-coding.

作者信息

He Shunmin, Liu Changning, Skogerbø Geir, Zhao Haitao, Wang Jie, Liu Tao, Bai Baoyan, Zhao Yi, Chen Runsheng

机构信息

Bioinformatics Laboratory and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

出版信息

Nucleic Acids Res. 2008 Jan;36(Database issue):D170-2. doi: 10.1093/nar/gkm1011. Epub 2007 Nov 13.

Abstract

The NONCODE database is an integrated knowledge database designed for the analysis of non-coding RNAs (ncRNAs). Since NONCODE was first released 3 years ago, the number of known ncRNAs has grown rapidly, and there is growing recognition that ncRNAs play important regulatory roles in most organisms. In the updated version of NONCODE (NONCODE v2.0), the number of collected ncRNAs has reached 206 226, including a wide range of microRNAs, Piwi-interacting RNAs and mRNA-like ncRNAs. The improvements brought to the database include not only new and updated ncRNA data sets, but also an incorporation of BLAST alignment search service and access through our custom UCSC Genome Browser. NONCODE can be found under http://www.noncode.org or http://noncode.bioinfo.org.cn.

摘要

NONCODE数据库是一个为分析非编码RNA(ncRNA)而设计的综合知识数据库。自从NONCODE于3年前首次发布以来,已知ncRNA的数量迅速增长,并且人们越来越认识到ncRNA在大多数生物体中发挥着重要的调控作用。在NONCODE的更新版本(NONCODE v2.0)中,收集到的ncRNA数量已达206226个,包括多种微小RNA、与Piwi相互作用的RNA以及类mRNA的ncRNA。该数据库带来的改进不仅包括新的和更新的ncRNA数据集,还纳入了BLAST比对搜索服务,并可通过我们定制的UCSC基因组浏览器进行访问。可在http://www.noncode.org或http://noncode.bioinfo.org.cn找到NONCODE。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9875/2238973/ba6fe5de5e72/gkm1011f1.jpg

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