NONCODEV6：一个更新的数据库，专门用于注释动植物中的长非编码 RNA。
NONCODEV6: an updated database dedicated to long non-coding RNA annotation in both animals and plants.
机构信息
Key Laboratory of Intelligent Information Processing, Advanced Computer Research Center, Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100190, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
出版信息
Nucleic Acids Res. 2021 Jan 8;49(D1):D165-D171. doi: 10.1093/nar/gkaa1046.
NONCODE (http://www.noncode.org/) is a comprehensive database of collection and annotation of noncoding RNAs, especially long non-coding RNAs (lncRNAs) in animals. NONCODEV6 is dedicated to providing the full scope of lncRNAs across plants and animals. The number of lncRNAs in NONCODEV6 has increased from 548 640 to 644 510 since the last update in 2017. The number of human lncRNAs has increased from 172 216 to 173 112. The number of mouse lncRNAs increased from 131 697 to 131 974. The number of plant lncRNAs is 94 697. The relationship between lncRNAs in human and cancer were updated with transcriptome sequencing profiles. Three important new features were also introduced in NONCODEV6: (i) updated human lncRNA-disease relationships, especially cancer; (ii) lncRNA annotations with tissue expression profiles and predicted function in five common plants; iii) lncRNAs conservation annotation at transcript level for 23 plant species. NONCODEV6 is accessible through http://www.noncode.org/.
NONCODE（http://www.noncode.org/）是一个全面的非编码 RNA （尤其是动物长非编码 RNA （lncRNA））收集和注释数据库。NONCODEV6 致力于提供植物和动物中全长 lncRNA 的信息。自 2017 年上次更新以来，NONCODEV6 中的 lncRNA 数量从 548640 增加到 644510。NONCODEV6 中的人类 lncRNA 数量从 172216 增加到 173112。小鼠 lncRNA 数量从 131697 增加到 131974。植物 lncRNA 数量为 94697。NONCODEV6 中还更新了人类 lncRNA 与癌症之间的关系，同时更新了转录组测序谱。NONCODEV6 还引入了三个重要的新功能：（i）更新的人类 lncRNA-疾病关系，尤其是癌症；（ii）具有组织表达谱和在五种常见植物中预测功能的 lncRNA 注释；（iii）23 种植物物种转录水平的 lncRNAs 保守注释。NONCODEV6 可通过 http://www.noncode.org/ 访问。
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