Suneja Tina, Flanagan Katherine H, Glaser Dee Anna
Denver Dermatology Consultants, Denver, CO, USA.
Dermatitis. 2007 Dec;18(4):208-11. doi: 10.2310/6620.2007.07013.
Nickel is a common cause of allergic contact dermatitis and is associated with metal buttons and snaps on blue jeans.
To determine the prevalence of nickel-positive metal buttons on blue jeans and the efficacy of nail polish in the prevention of nickel release.
We collected 62 pairs of new and preworn blue jeans. The metal buttons were tested for nickel with a dimethylglyoxime test kit, and one coat of clear nail polish was applied to nickel-positive buttons. Painted buttons were dried for 24 hours, and the jeans were washed on delicate cycle and retested for nickel. The jeans underwent a second wash/dry cycle and were retested.
The prevalence of nickel-positive metal buttons on blue jeans was 16%. Ten pairs of jeans tested positive for nickel. All 10 pairs tested negative for nickel after the application of one coat of clear nail polish. Of these 10 pairs, seven pairs underwent two wash/dry cycles, and all seven tested negative for nickel after each cycle.
The presence of nickel-positive blue-jean buttons is greater in new jeans than in preworn jeans. One clear coat of nail polish can prevent nickel release through two wash/dry cycles in a test environment.
镍是过敏性接触性皮炎的常见病因，与蓝色牛仔裤上的金属纽扣和按扣有关。
确定蓝色牛仔裤上镍阳性金属纽扣的患病率以及指甲油预防镍释放的效果。
我们收集了62条新的和穿旧的蓝色牛仔裤。用丁二酮肟测试试剂盒对金属纽扣进行镍检测，并在镍阳性纽扣上涂一层透明指甲油。涂漆的纽扣干燥24小时，牛仔裤以轻柔模式洗涤并再次进行镍检测。牛仔裤经过第二次洗涤/干燥循环并再次进行检测。
蓝色牛仔裤上镍阳性金属纽扣的患病率为16%。10条牛仔裤镍检测呈阳性。在涂一层透明指甲油后，所有10条牛仔裤镍检测均呈阴性。在这10条牛仔裤中，7条经过了两个洗涤/干燥循环，并且在每个循环后所有7条镍检测均呈阴性。
新牛仔裤中镍阳性蓝色牛仔裤纽扣的存在比穿旧的牛仔裤更多。在测试环境中，一层透明指甲油可以防止镍在两个洗涤/干燥循环中释放。
