Faerden Ann, Nesvåg Ragnar, Barrett Elizabeth Ann, Agartz Ingrid, Finset Arnstein, Friis Svein, Rossberg Jan Ivar, Melle Ingrid
Section for Psychosis Research, Division of Psychiatry, Building 49, Ullevål University Hospital, Krikeveien 166, 0407 Oslo, Norway.
Eur Psychiatry. 2008 Jan;23(1):33-9. doi: 10.1016/j.eurpsy.2007.09.002. Epub 2007 Oct 29.
Recently there has been a renewed interest in defining the boundaries and subdomains of the negative syndrome in schizophrenia and new scales have been asked for. Apathy is one of the symptoms in focus. The Apathy Evaluation Scale (AES) with its clinical version (AES-C) is one of the most used scales in an interdisciplinary context, but it has never previously been used in a population with first episode psychosis. The main aims of this study were to examine the psychometric properties of the AES-C and its relationship to the Positive and Negative Syndrome Scale (PANSS).
A total of 104 patients with first episode psychosis from the ongoing Thematic Organized Psychosis Research (TOP) study were included.
A factor analysis of the AES-C identified three subscales: Apathy, Insight and Social Contacts. Only the Apathy subscale showed satisfactory psychometric properties and showed acceptable convergent and discriminate properties by correlating strongly with the apathy-related items of the PANSS.
This study shows that the AES-C measures more than one dimension. The main factor, the Apathy subscale, can however be used to assess apathy in first episode psychosis patients in the ongoing work of refining the subdomains of the negative syndrome.
最近，人们对界定精神分裂症阴性症状的边界和子领域重新产生了兴趣，并需要新的量表。冷漠是其中一个重点关注的症状。冷漠评估量表（AES）及其临床版本（AES-C）是跨学科背景下使用最广泛的量表之一，但此前从未在首发精神病患者群体中使用过。本研究的主要目的是检验AES-C的心理测量特性及其与阳性和阴性症状量表（PANSS）的关系。
纳入了正在进行的主题性有组织精神病研究（TOP）中的104例首发精神病患者。
对AES-C进行的因素分析确定了三个子量表：冷漠、洞察力和社交接触。只有冷漠子量表显示出令人满意的心理测量特性，并通过与PANSS中与冷漠相关的项目高度相关，显示出可接受的收敛性和区分性特性。
本研究表明，AES-C测量的不止一个维度。然而，主要因素，即冷漠子量表，可用于在完善阴性症状子领域的当前工作中评估首发精神病患者的冷漠情况。
