Hayashi K, Kurisu Y, Ohshiba S, Kawamura H, Furutama D, Takada K, Shimamoto C, Matsumoto T, Hirata I
Second Department of Internal Medicine, Osaka Medical College, Japan.
Jpn J Med. 1991 Sep-Oct;30(5):441-5. doi: 10.2169/internalmedicine1962.30.441.
A young male patient with myositis associated with Crohn's disease is reported. His serum creatine phosphokinase (CPK) level was markedly elevated, but he had no muscle symptoms. The serum CPK level was not correlated with the activity of Crohn's disease. Muscle biopsy showed myositis with only degeneration of the muscle fibers and infiltration of inflammatory cells. The etiology of myositis in this case was not clear. Diagnosis of myositis based on a muscle biopsy in patients with Crohn's disease showing an elevated serum CPK level without any discernible cause has not been reported previously. Careful attention to the serum CPK and muscle symptoms in patients with Crohn's disease is suggested.
报道了一名患有与克罗恩病相关的肌炎的年轻男性患者。他的血清肌酸磷酸激酶（CPK）水平显著升高，但他没有肌肉症状。血清CPK水平与克罗恩病的活动度无关。肌肉活检显示为肌炎，仅有肌纤维变性和炎症细胞浸润。该病例中肌炎的病因尚不清楚。此前尚未有关于在克罗恩病患者中，基于肌肉活检诊断肌炎，且血清CPK水平升高但无任何可识别病因的报道。建议对克罗恩病患者的血清CPK和肌肉症状予以密切关注。
