Leibowitz G, Eliakim R, Amir G, Rachmilewitz D
Department of Medicine, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel.
J Clin Gastroenterol. 1994 Jan;18(1):48-52. doi: 10.1097/00004836-199401000-00012.
A 29-year-old woman with quiescent Crohn's disease developed severe myositis. Serum creatine phosphokinase was markedly elevated, and muscle biopsy showed typical findings of dermatomyositis. The muscular symptoms promptly responded to combined treatment with corticosteroids and azathioprine. The association between inflammatory bowel disease and inflammatory myopathies is very rare. We review the clinical, pathological, and pathophysiological aspects of this association.
一名患有静止期克罗恩病的29岁女性出现了严重的肌炎。血清肌酸磷酸激酶显著升高,肌肉活检显示皮肌炎的典型表现。肌肉症状对皮质类固醇和硫唑嘌呤的联合治疗迅速产生反应。炎症性肠病与炎症性肌病之间的关联非常罕见。我们回顾了这种关联的临床、病理和病理生理方面。