Ren Hongwu, Ding Zhihua, Zhao Yonghua, Miao Jianjun, Nelson J Stuart, Chen Zhongping
Opt Lett. 2002 Oct 1;27(19):1702-4. doi: 10.1364/ol.27.001702.
We describe a phase-resolved functional optical coherence tomography system that can simultaneously yieldin situ images of tissue structure, blood flow velocity, standard deviation, birefringence, and the Stokes vectors in human skin. Multifunctional images were obtained by processing of analytical interference fringe signals derived from two perpendicular polarization-detection channels. The blood flow velocity and standard deviation images were obtained by comparison of the phases from pairs of analytical signals in neighboring A-lines in the same polarization state. The analytical signals from two polarization-diversity detection channels were used to determine the four Stokes vectors for four reference polarization states. From the four Stokes vectors, the birefringence image, which is not sensitive to the orientation of the optical axis in the sample, was obtained. Multifunctional in situ images of a port wine stain birthmark in human skin are presented.
我们描述了一种相位分辨功能光学相干断层扫描系统，该系统能够同时获取人体皮肤组织结构、血流速度、标准差、双折射以及斯托克斯矢量的原位图像。通过处理来自两个垂直偏振检测通道的解析干涉条纹信号获得多功能图像。血流速度和标准差图像是通过比较相同偏振态下相邻A线中解析信号对的相位得到的。来自两个偏振分集检测通道的解析信号用于确定四个参考偏振态的四个斯托克斯矢量。从这四个斯托克斯矢量中，获得了对样品中光轴方向不敏感的双折射图像。展示了人体皮肤葡萄酒色斑胎记的多功能原位图像。
