Caratozzolo E, Massani M, Recordare A, Bonariol L, Baldessin M, Bassi N
Regional Hospital Cà Foncello, Treviso, Italy.
G Chir. 2007 Nov-Dec;28(11-12):419-24.
to identify the factors that could influence the outcome of the old aged patients underwent liver resection for hepatocellular carcinoma (HCC) or colorectal liver metastases (LMCRC).
the Authors identified 51 patients older 70 years-old over 12-years period underwent resection for HCC (n 26) or for LMCRC (n 25). This group was compared with a cohort of 93 patients younger than 70 years who underwent resections in the same period. We have evaluated the results in terms of peroperative morbidity and mortality.
the mean age of 51 elderly patients was 74 years-old. Thirty-five were treated with anatomical resection. Cirrhosis was present in 26 patients while 27 had co-morbidities. Thirteen patients developed complications and the mean age of these were 76 years compared with 73 of the patients who have not (p= .01). No mortality was registered. The cirrhosis, blood transfusions, anatomical resection and diameter of the lesion did not influence the outcome.
our results indicate the age per se should not be considered a contraindication for surgery, that proved to be safe and curative therapy, but showed that old age, using 75 years as a cut-off, in association with at least one comorbid medical condition could be considered as relevant factor of morbidity.
确定可能影响老年患者肝细胞癌（HCC）或结直肠癌肝转移（LMCRC）肝切除术后结局的因素。
作者在12年期间确定了51例年龄超过70岁的患者，他们接受了HCC（n = 26）或LMCRC（n = 25）的切除术。将该组与同期接受手术的93例年龄小于70岁的患者队列进行比较。我们从手术发病率和死亡率方面评估了结果。
51例老年患者的平均年龄为74岁。35例行解剖性切除。26例患者存在肝硬化，27例有合并症。13例患者出现并发症，这些患者的平均年龄为76岁，而未出现并发症的患者平均年龄为73岁（p = 0.01）。无死亡病例记录。肝硬化、输血、解剖性切除和病变直径均不影响结局。
我们的结果表明，年龄本身不应被视为手术禁忌证，手术被证明是安全且有效的治疗方法，但表明以75岁为界，老年患者若伴有至少一种合并症，可被视为发病的相关因素。
