Ermolenko E I, Chernysh A Iu, Martsinkovskaia I V, Suvorov A N
Zh Mikrobiol Epidemiol Immunobiol. 2007 Sep-Oct(5):73-7.
Individual features of sensitivity of some strains of group B streptococci (GBS) to influence of 2 probiotic cultures of Enterococcus faecium (SF68 and L3) have been studied by double agar test. E. faecium L3 strain had higher antagonistic activity to GBS. Two genes encoding enterocins A and B as well as genes responsible for the expression of the former two genes were found in the genome of this strain. The supernatant and peptide extract of E. faecium L3 contained thermostable low molecular weight peptides which inhibited growth of listeria and GBS but at lesser extent compared with native enterococci. Obtained data allow to suggest that antagonistic activity of enterococci against GBS may be affiliated with production of enterocins A and B and can be increased by the presence of other metabolites.
通过双层琼脂试验研究了某些B组链球菌（GBS）菌株对两种屎肠球菌益生菌培养物（SF68和L3）影响的敏感性个体特征。屎肠球菌L3菌株对GBS具有更高的拮抗活性。在该菌株的基因组中发现了两个编码肠球菌素A和B的基因以及负责前两个基因表达的基因。屎肠球菌L3的上清液和肽提取物含有热稳定的低分子量肽，其抑制李斯特菌和GBS的生长，但与天然肠球菌相比程度较小。获得的数据表明，肠球菌对GBS的拮抗活性可能与肠球菌素A和B的产生有关，并且可以通过其他代谢产物的存在而增加。
