Stockwell T, Bolt L, Milner I, Russell G, Bolderston H, Pugh P
Exeter Drug and Alcohol Resource Team, Devon, U.K.
Alcohol Alcohol. 1991;26(5-6):645-50. doi: 10.1093/oxfordjournals.alcalc.a045169.
The safety and short-term effectiveness of home detoxification (HD) was investigated by contrasting rates of treatment completion and of complications of 41 service users with those of a retrospectively matched inpatient comparison group. The latter comprised patients of a detoxification unit matched for age, sex and degree of alcohol dependence with HD subjects. HD subjects had severe problems with alcohol--they averaged 28.7 on the SADQ, 4.6 serious alcohol-related problems in the previous 2 months, a GGT of 123.8 and 174.6 reported units of alcohol consumed in the week before treatment. A high follow-up rate was achieved for both HD subjects and their relatives; there was close agreement between clients' reports, carers' reports and breathalyser readings with regard to further alcohol consumption. The HD subjects were visited at home an average of 6.9 times over 6.15 days. Chlormethiazole was prescribed in 36 cases at an average maximum daily dose of 6.3 capsules--significantly fewer than for the inpatient group. Both rates of completion and complication were virtually identical in the 2 groups. It is concluded that these data suggest HD is equivalent in both its safety and immediate efficacy to more expensive inpatient care.
通过对比41名服务使用者的治疗完成率和并发症发生率与回顾性匹配的住院对照组的情况，对家庭戒毒（HD）的安全性和短期有效性进行了调查。后者由戒毒单元中年龄、性别和酒精依赖程度与HD受试者相匹配的患者组成。HD受试者存在严重的酒精问题——他们在酒精依赖自评问卷（SADQ）上的平均得分是28.7分，在前两个月中有4.6个严重的酒精相关问题，γ-谷氨酰转移酶（GGT）为123.8，治疗前一周报告的酒精摄入量为174.6单位。HD受试者及其亲属的随访率很高；在客户报告、护理人员报告和呼气酒精含量读数之间，关于进一步饮酒情况的一致性很高。HD受试者在6.15天内平均接受了6.9次家访。36例患者开具了氯美噻唑，平均最大日剂量为6.3粒胶囊——明显少于住院组。两组的完成率和并发症发生率几乎相同。结论是，这些数据表明HD在安全性和即时疗效方面与更昂贵的住院治疗相当。
