Murakami N, Morimoto T, Imamura H, Ueda T, Nagai S, Sakakibara J, Yamada N
Faculty of Pharmaceutical Sciences, Nagoya City University, Japan.
Chem Pharm Bull (Tokyo). 1991 Sep;39(9):2277-81. doi: 10.1248/cpb.39.2277.
Seven new monogalactosyl diacylglycerols (1-7) and six new digalactosyl diacylglycerols (11-16) were isolated from an axenically cultured cyanobacterium, P. tenue. Their structures were elucidated on the basis of physicochemical evidence and the results of enzymatic hydrolysis using a lipase (from Rhizopus arrhizus). Comparison of antialgal activity for P. tenue between monogalactosyl diacylglycerols (1-8) and digalactosyl diacylglycerols (11-19) revealed that the former showed more potent activity than the latter.
从无菌培养的蓝藻纤细席藻（P. tenue）中分离出7种新的单半乳糖基二酰基甘油（1-7）和6种新的双半乳糖基二酰基甘油（11-16）。基于物理化学证据和使用脂肪酶（来自米根霉）进行酶水解的结果阐明了它们的结构。比较单半乳糖基二酰基甘油（1-8）和双半乳糖基二酰基甘油（11-19）对纤细席藻的抗藻活性，结果表明前者的活性比后者更强。
