Nemchinov Lev G, Shabala Lana, Shabala Sergey
USDA/ARS, Plant Sciences Institute, Molecular Plant Pathology Laboratory, Beltsville, MD 20705, USA.
Plant Cell Physiol. 2008 Jan;49(1):40-6. doi: 10.1093/pcp/pcm163. Epub 2007 Nov 29.
Using a model plant Nicotiana benthamiana, we have demonstrated that initial calcium uptake in response to the HR (hypersensitive response)-causing pathogen Pseudomonas syringae pv syringae 61 is followed by net calcium efflux initiated at about 12 h after the bacterial challenge and sustained for at least 48 h. Our data suggest that calcium not only acts as an important second messenger in the activation of resistance responses but may also be a downstream mediator of later cell death acceleration and completion of the defense reaction. Accordingly, we propose that the existing model of HR should be amended to include a PM Ca(2+) ATP pump as an important component of the HR to pathogens in plants.
利用模式植物本氏烟草，我们已经证明，在对引起过敏反应（HR）的病原菌丁香假单胞菌丁香致病变种61的应答中，最初的钙摄取之后是在细菌攻击后约12小时开始并持续至少48小时的净钙外流。我们的数据表明，钙不仅在抗性反应激活中作为重要的第二信使起作用，而且可能也是后期细胞死亡加速和防御反应完成的下游介质。因此，我们建议应修改现有的HR模型，将质膜Ca(2+) ATP酶作为植物对病原体HR的重要组成部分。
