Kandel D B
Columbia University, Department of Psychiatry, New York, NY 10032.
Milbank Q. 1991;69(3):365-414.
This review of the epidemiology of drug use and drug dependence/abuse describes the overall current pattern of use of mood-changing legal and illegal drugs based on the most recently available data, variations in drug use among subgroups in the population, and trends in drug use over time. This is the first systematic attempt to integrate data on patterns of use with data on drug dependence/abuse. In the course of the analysis an effort is made to account for two paradoxes: blacks report the lowest rate of drug use in general population studies, yet constitute the largest category of treated cases or drug-related casualties. Although prevalence of cocaine use in the general population decreased, beginning in 1986, morbidity and mortality related to cocaine increased sharply in 1990.
本关于药物使用及药物依赖/滥用的流行病学综述,依据最新可得数据,描述了改变情绪的合法及非法药物的当前总体使用模式、人群中不同亚组间药物使用的差异以及药物使用随时间的趋势。这是首次将药物使用模式数据与药物依赖/滥用数据进行系统整合的尝试。在分析过程中,努力解释两个矛盾现象:在一般人群研究中,黑人报告的药物使用率最低,但却是接受治疗病例或与药物相关伤亡的最大类别。尽管自1986年起,一般人群中可卡因的使用率有所下降,但1990年与可卡因相关的发病率和死亡率却急剧上升。