Jang Yun-Woo, Lee In-Kyoung, Kim Young-Sook, Lee Sangku, Lee Ho-Jae, Yu Seung Hun, Yun Bong-Sik
Korea Research Institute of Bioscience and Biotechnology, Yuseong-gu, Daejeon, Korea.
J Antibiot (Tokyo). 2007 Nov;60(11):696-9. doi: 10.1038/ja.2007.89.
Two new polypropionates designated as xylarinic acids A and B were isolated from the fruiting body of Xylaria polymorpha. Their structures were established as 4,6,8-trimethyl-2,4-decadienoic acid and 2,4,6-trimethyl-2-octenoic acid, respectively, on the basis of extensive spectroscopic analysis. Both compounds displayed significant antifungal activity against plant pathogenic fungi Pythium ultinum, Magnaporthe grisea, Aspergillus niger, Alternaria panax, and Fusarium oxysporium, whereas they did not show antibacterial and cytotoxic effect.
