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自闭症诊断访谈修订版在自闭症谱系障碍儿童从学前到小学阶段的稳定性。

Stability of the autism diagnostic interview-revised from pre-school to elementary school age in children with autism spectrum disorders.

作者信息

Moss Jo, Magiati Iliana, Charman Tony, Howlin Patricia

机构信息

Department of Community Health Sciences, St George's, University of London, London, UK.

出版信息

J Autism Dev Disord. 2008 Jul;38(6):1081-91. doi: 10.1007/s10803-007-0487-9. Epub 2007 Dec 6.

Abstract

This study examined the stability of scores on the ADI-R from pre-school to elementary school age in children with autism spectrum disorders (ASD). Participants were 35 children who, at T1, all had a clinical diagnosis of ASD. On initial assessment (mean age 3.5 years; SD 0.6 years), all met ADI-R algorithm criteria for autism. ADI-R assessments were repeated at follow up (FU; mean age 10.5 years; SD 0.8 years). Changes in ADI-R total, domain and ADI-R algorithm item scores were assessed. Twenty-eight children continued to score above the ADI-R cut-off for autism at FU, although significant decreases in ADI-R domain and item scores were also found. In conclusion while classification of children according to ADI-R criteria generally remained stable between pre-school and elementary school age, many children demonstrated significant improvements in symptom severity.

摘要

本研究考察了自闭症谱系障碍(ASD)儿童从学前到小学阶段的孤独症诊断访谈修订版(ADI-R)评分的稳定性。研究对象为35名儿童,在T1时,他们均被临床诊断为ASD。在初次评估时(平均年龄3.5岁;标准差0.6岁),所有儿童均符合ADI-R自闭症诊断标准。在随访时(FU;平均年龄10.5岁;标准差0.8岁)重复进行ADI-R评估。评估了ADI-R总分、领域分和ADI-R诊断标准项目得分的变化。28名儿童在随访时的ADI-R得分仍高于自闭症诊断临界值,不过也发现ADI-R领域分和项目得分有显著下降。总之,虽然根据ADI-R标准对儿童的分类在学前到小学阶段总体保持稳定,但许多儿童的症状严重程度有显著改善。

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