Theysohn Jens M, Maderwald Stefan, Kraff Oliver, Moenninghoff Christoph, Ladd Mark E, Ladd Susanne C
Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany.
MAGMA. 2008 Mar;21(1-2):63-72. doi: 10.1007/s10334-007-0095-x. Epub 2007 Dec 7.
One prerequisite for transferring ultra-high-field magnetic resonance imaging (MRI) (>3T) into clinical diagnostic workup is a low rate of side effects. To our knowledge, publications of subjective acceptance and willingness to undergo examinations at >3T are rare. We present first results from our research site.
Exposure to 7 T whole-body MRI of head, extremities, or breast was assessed in 102 subjects. They judged sources of discomfort (examination duration, room temperature) and physiological sensations (vertigo, light flashes) on a 10-point scale, differentiating between examination phases: table stationary or moving. For comparison, the same questionnaire was completed by 43 of these subjects after undergoing a 1.5 T examination. Vertigo was the most pronounced sensation at 7 T with 5% rating it as very unpleasant (none at 1.5 T). This should be compared with the fact that the lengthy exam duration was regarded as even more uncomfortable. Compared to 1.5 T, average study duration at 7 T was roughly doubled, and 7 T elicited a wider range of complaints.
Although the number of side effects is increased at 7 T compared to 1.5 T, 7 T was well tolerated by the majority of subjects. Further data collection is necessary for better understanding of these effects.
将超高场磁共振成像(MRI)(>3T)应用于临床诊断检查的一个前提条件是副作用发生率低。据我们所知,关于在>3T场强下进行检查的主观接受度和意愿的相关文献很少。我们展示了我们研究地点的首批结果。
对102名受试者进行了头部、四肢或乳房的7T全身MRI检查。他们根据10分制对不适来源(检查持续时间、室温)和生理感觉(眩晕、闪光)进行评分,区分检查阶段:检查台静止或移动。作为对照,其中43名受试者在接受1.5T检查后填写了相同的问卷。眩晕是7T场强下最明显的感觉,5%的受试者将其评为非常不舒服(1.5T场强下无人有此感觉)。这应与检查持续时间过长被认为更不舒服这一事实相比较。与1.5T相比,7T的平均检查时间大约翻倍,且7T引发的抱怨更多。
尽管与1.5T相比,7T的副作用数量有所增加,但大多数受试者对7T的耐受性良好。为了更好地了解这些影响,有必要进一步收集数据。