小鼠和斑马鱼眼睛中的透明晶状体和角膜。
The transparent lens and cornea in the mouse and zebra fish eye.
作者信息
Greiling Teri M S, Clark John I
机构信息
University of Washington, Seattle, WA 98195-7420, USA.
出版信息
Semin Cell Dev Biol. 2008 Apr;19(2):94-9. doi: 10.1016/j.semcdb.2007.10.011. Epub 2007 Oct 30.
The lens and cornea combine to form a single optical element in which transparency and refraction are the fundamental biophysical characteristics required for a functional visual system. Although lens and cornea have different cellular and extracellular specializations that contribute to transparency and refraction, their development is closely related. In the embryonic mouse, the developing cornea and lens separate early. In contrast, zebra fish lens and cornea remain connected during early development and the optical properties of the cornea and lens observed by slit lamp and quasielastic laser light scattering spectroscopy (QLS) are more similar in the zebra fish eye than in the mouse eye. Optical similarities between cornea and lens of zebra fish may be the result of similarities in the cellular development of the cornea and lens.
晶状体和角膜共同构成一个单一的光学元件，其中透明度和折射是功能性视觉系统所需的基本生物物理特性。尽管晶状体和角膜具有不同的细胞和细胞外特化结构，这些结构有助于实现透明度和折射，但它们的发育密切相关。在胚胎小鼠中，发育中的角膜和晶状体很早就分开了。相比之下，斑马鱼的晶状体和角膜在早期发育过程中保持相连，并且通过裂隙灯和准弹性激光光散射光谱法（QLS）观察到的斑马鱼眼睛中角膜和晶状体的光学特性比小鼠眼睛中的更为相似。斑马鱼角膜和晶状体之间的光学相似性可能是角膜和晶状体细胞发育相似的结果。
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