Dinman Jonathan D
Department of Cell Biology and Molecular Genetics, Microbiology Building Room 2135, University of Maryland, College Park, MD 20742.
Int J Biomed Sci. 2005 Jun;1(1):2-7.
5S rRNA is uniquely positioned so as to link together all of the functional centers of the ribosome. Previous studies have supported the hypothesis that 5S rRNA acts as a physical transducer of information, facilitating communication between the different functional centers and coordinating of the multiple events catalyzed by the ribosome. Here, we present a synthesis of both structural and genetic information to construct a more detailed picture of how 5S rRNA may act to transmit and coordinate all of the functional centers of the ribosome.
5S核糖体RNA处于独特的位置，能够将核糖体的所有功能中心连接在一起。先前的研究支持这样一种假说，即5S核糖体RNA作为信息的物理传递者，促进不同功能中心之间的交流，并协调核糖体催化的多个事件。在这里，我们综合结构和遗传信息，构建出一幅更详细的图景，以说明5S核糖体RNA可能如何发挥作用来传递和协调核糖体的所有功能中心。
