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新型隐球菌葡糖木聚糖在MVista组织胞浆菌抗原酶免疫测定中不表现出交叉反应性。

Cryptococcal glucoxylomannan does not exhibit cross-reactivity in the MVista Histoplasma antigen enzyme immunoassay.

作者信息

Zhuang David, Hage Chadi, De Jesus Magdia, Hackett Emily, Durkin Michelle, Davis Thomas E, Casadevall Arturo, Wheat L Joseph

机构信息

MiraVista Diagnostics, Indianapolis, Indiana 46241, USA.

出版信息

Clin Vaccine Immunol. 2008 Feb;15(2):392-3. doi: 10.1128/CVI.00383-07. Epub 2007 Dec 12.

Abstract

The potential for cross-reaction between Cryptococcus neoformans and Histoplasma capsulatum in antigen assays was evaluated. We tested patient samples, spleens from infected mice, and purified polysaccharides in the MVista Histoplasma antigen enzyme immunoassay and cryptococcal antigen latex agglutination system for cross-reactivity, and none was observed.

摘要

评估了新型隐球菌和荚膜组织胞浆菌在抗原检测中发生交叉反应的可能性。我们在MVista组织胞浆菌抗原酶免疫测定和隐球菌抗原乳胶凝集系统中检测了患者样本、感染小鼠的脾脏以及纯化的多糖的交叉反应性,未观察到交叉反应。

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