抗体在宿主对疏螺旋体感染的反应中所起的重要且多样的作用。
The important and diverse roles of antibodies in the host response to Borrelia infections.
作者信息
LaRocca T J, Benach J L
机构信息
Center for Infectious Diseases, 5120 Centers for Molecular Medicine, Stony Brook, NY 11794-5120, USA.
出版信息
Curr Top Microbiol Immunol. 2008;319:63-103. doi: 10.1007/978-3-540-73900-5_4.
PMID:18080415
Abstract
Antibodies are of critical importance in the host response to tick-borne Borrelia species that cause relapsing fever and Lyme disease. Recent studies on the role of various B cell subsets in the host response to Borrelia, complement-independent, bactericidal antibodies, and diagnostics led to this review that focuses on the array of functions that antibodies to Borrelia can perform.
摘要
抗体在宿主对引起回归热和莱姆病的蜱传疏螺旋体物种的反应中至关重要。最近关于各种B细胞亚群在宿主对疏螺旋体的反应、补体非依赖性杀菌抗体及诊断方面作用的研究促成了本综述，该综述聚焦于抗疏螺旋体抗体所能发挥的一系列功能。
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