Karolchik D, Kuhn R M, Baertsch R, Barber G P, Clawson H, Diekhans M, Giardine B, Harte R A, Hinrichs A S, Hsu F, Kober K M, Miller W, Pedersen J S, Pohl A, Raney B J, Rhead B, Rosenbloom K R, Smith K E, Stanke M, Thakkapallayil A, Trumbower H, Wang T, Zweig A S, Haussler D, Kent W J
Center for Biomolecular Science and Engineering, University of California Santa Cruz (UCSC), Santa Cruz, CA 95064, USA.
Nucleic Acids Res. 2008 Jan;36(Database issue):D773-9. doi: 10.1093/nar/gkm966. Epub 2007 Dec 17.
The University of California, Santa Cruz, Genome Browser Database (GBD) provides integrated sequence and annotation data for a large collection of vertebrate and model organism genomes. Seventeen new assemblies have been added to the database in the past year, for a total coverage of 19 vertebrate and 21 invertebrate species as of September 2007. For each assembly, the GBD contains a collection of annotation data aligned to the genomic sequence. Highlights of this year's additions include a 28-species human-based vertebrate conservation annotation, an enhanced UCSC Genes set, and more human variation, MGC, and ENCODE data. The database is optimized for fast interactive performance with a set of web-based tools that may be used to view, manipulate, filter and download the annotation data. New toolset features include the Genome Graphs tool for displaying genome-wide data sets, session saving and sharing, better custom track management, expanded Genome Browser configuration options and a Genome Browser wiki site. The downloadable GBD data, the companion Genome Browser toolset and links to documentation and related information can be found at: http://genome.ucsc.edu/.
加州大学圣克鲁兹分校基因组浏览器数据库（GBD）为大量脊椎动物和模式生物基因组提供了整合的序列和注释数据。在过去一年中，已有17个新的基因组装配被添加到该数据库，截至2007年9月，数据库总共涵盖了19种脊椎动物和21种无脊椎动物的基因组。对于每个基因组装配，GBD都包含了一系列与基因组序列比对的注释数据。今年新增内容的亮点包括一个基于28个物种的人类脊椎动物保守性注释、一个增强的加州大学圣克鲁兹分校基因集，以及更多的人类变异、MGC和ENCODE数据。该数据库通过一套基于网络的工具进行了优化，以实现快速的交互性能，这些工具可用于查看、操作、筛选和下载注释数据。新的工具集功能包括用于显示全基因组数据集的基因组图谱工具、会话保存和共享、更好的自定义轨道管理、扩展的基因组浏览器配置选项以及一个基因组浏览器维基网站。可通过以下网址获取可下载的GBD数据、配套的基因组浏览器工具集以及文档和相关信息的链接：http://genome.ucsc.edu/ 。
