Hayes Alan, Cribb Paul J
Exercise Metabolism Unit, Center for Aging, Rehabilitation, Exercise and Sport (CARES) and School of Biomedical Sciences, Victoria University, Victoria, Australia.
Curr Opin Clin Nutr Metab Care. 2008 Jan;11(1):40-4. doi: 10.1097/MCO.0b013e3282f2a57d.
Sarcopenia (skeletal muscle wasting with aging) is thought to underlie a number of serious age-related health issues. While it may be seen as inevitable, decreasing this gradual loss of muscle is vital for healthy aging. Thus, it is imperative to investigate exercise and nutrition-based strategies designed to build a reservoir of muscle mass as early as possible.
Elderly individuals are still able to respond to both resistance training and the anabolic signals provided by protein ingestion, provided specific amino acids, such as leucine, are present. Whey proteins are a rich source of these essential amino acids and rapidly elevate plasma amino acids, thus providing the foundations for preservation of muscle mass. Several studies involving supplementation with whey protein have been shown to be effective in augmenting the effects of resistance exercise, particularly when supplementation occurs in the hours surrounding the exercise training.
While further work is required, particularly in elderly people, simple dietary and exercise strategies that may improve the maintenance of skeletal muscle mass will likely result in a decrease in the overall burden of a number of diseases and improve the quality of life as we age.
肌肉减少症(随着年龄增长出现的骨骼肌萎缩)被认为是许多严重的与年龄相关的健康问题的根源。虽然它可能被视为不可避免,但减少这种逐渐的肌肉流失对于健康老龄化至关重要。因此,迫切需要研究基于运动和营养的策略,旨在尽早建立肌肉量储备。
老年人仍然能够对阻力训练以及蛋白质摄入(前提是存在特定氨基酸,如亮氨酸)所提供的合成代谢信号做出反应。乳清蛋白是这些必需氨基酸的丰富来源,并能迅速提高血浆氨基酸水平,从而为维持肌肉量奠定基础。几项涉及补充乳清蛋白的研究已表明,这在增强阻力运动的效果方面是有效的,特别是当在运动训练前后数小时内进行补充时。
虽然还需要进一步的研究,特别是在老年人中,但简单的饮食和运动策略可能有助于维持骨骼肌量,这可能会减轻多种疾病的总体负担,并随着年龄增长提高生活质量。