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创伤后应激障碍的筛查:哪种症状组合预测效果最佳?

Screening for posttraumatic stress disorder: what combination of symptoms predicts best?

作者信息

Ehring Thomas, Kleim Birgit, Clark David M, Foa Edna B, Ehlers Anke

机构信息

Department of Psychology, Institute of Psychiatry, King's College London, London, United Kingdom.

出版信息

J Nerv Ment Dis. 2007 Dec;195(12):1004-12. doi: 10.1097/NMD.0b013e31815c1999.

DOI:10.1097/NMD.0b013e31815c1999
PMID:18091194
Abstract

Several symptom screening instruments have been developed to identify trauma survivors at risk for chronic posttraumatic stress disorder, but few of these have been thoroughly evaluated to date. In this study, a range of symptom combination scoring rules derived from the literature were applied to the Posttraumatic Diagnostic Scale and evaluated in 4 different samples of trauma survivors (total N = 522) regarding their power to identify people with posttraumatic stress disorder. Results were replicated in a fifth sample (N = 253). Most scoring rules showed lower diagnostic efficiencies than in the original reports. The most stable results were obtained for cutoffs on the Posttraumatic Diagnostic Scale total scale and a new subset of 8 items. The results underscore the need to cross-validate findings before using screening instruments for clinical applications.

摘要

已经开发了几种症状筛查工具来识别有患慢性创伤后应激障碍风险的创伤幸存者,但迄今为止,对其中很少一部分进行过全面评估。在本研究中,将一系列从文献中得出的症状组合评分规则应用于创伤后诊断量表,并在4个不同的创伤幸存者样本(总计N = 522)中评估其识别创伤后应激障碍患者的能力。结果在第五个样本(N = 253)中得到了重复验证。大多数评分规则显示出比原始报告中更低的诊断效率。创伤后诊断量表总分和一个新的8项子集的临界值获得了最稳定的结果。这些结果强调了在将筛查工具用于临床应用之前对研究结果进行交叉验证的必要性。

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