Moodley J
Women's Health and HIV Research Group, Nelson R Mandela School of Medicine, Durban.
Cardiovasc J Afr. 2007 Nov-Dec;18(6):358-61.
Hypertensive disorders of pregnancy (proteinuric hypertension, eclampsia, chronic hypertension, HELL P syndrome) are the commonest direct causes of maternal deaths in South Africa. Six hundred and twenty-eight (19.1%) of the 3 406 maternal deaths in a three-year period (2002-2004) were associated with hypertensive disorders of pregnancy. Cerebral complications, mainly cerebral haemorrhage, were the pathological causes of death in approximately 50% of the cases and eclampsia (convulsions in pregnancy associated with high blood pressure) was the commonest clinical condition leading to death from hypertension. Avoidable factors, missed opportunities and substandard care in all three categories of patient-related, administrative, and healthcare-related components were found by the assessors of the National Committee on Confidential Enquiries into Maternal Deaths to be prevalent in the majority of the deaths. Prevention of complications by lowering high blood pressure fairly rapidly, early referral of high-risk cases to experts in the field, and the proper use of resuscitation skills should reduce maternal mortality associated with hypertensive disorders of pregnancy.
妊娠高血压疾病(蛋白尿性高血压、子痫、慢性高血压、HELLP综合征)是南非孕产妇死亡最常见的直接原因。在三年期间(2002 - 2004年)的3406例孕产妇死亡中,有628例(19.1%)与妊娠高血压疾病相关。脑部并发症,主要是脑出血,是约50%病例的病理死因,子痫(妊娠期间与高血压相关的惊厥)是导致高血压死亡最常见的临床情况。国家孕产妇死亡保密调查委员会的评估人员发现,在大多数死亡病例中,与患者相关、行政和医疗保健相关的所有三类因素中,可避免因素、错失的机会和不合格护理普遍存在。通过相当迅速地降低高血压来预防并发症、将高危病例尽早转诊给该领域的专家以及正确使用复苏技能,应能降低与妊娠高血压疾病相关的孕产妇死亡率。