Silvares Maria Regina Cavariani, Coelho Kunie Iabuki Rabello, Dalben Ivete, Lastória Joel Carlos, Abbade Luciana Patrícia Fernandes
Hospital das Clínicas, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
Sao Paulo Med J. 2007 Sep 6;125(5):281-5. doi: 10.1590/s1516-31802007000500006.
Chronic urticaria-angioedema is a common, multiple-cause complaint. The aim was to investigate the sociodemographic and clinical characteristics, causal and aggravating factors and evolution of urticaria-angioedema.
This was a descriptive prospective study carried out at the Dermatology outpatient clinic of Faculdade de Medicina de Botucatu, Universidade Estadual Paulista (Unesp).
A total of 125 patients with chronic urticaria-angioedema were evaluated to obtain sociodemographic data, anamnesis, dermatological and general clinical data and laboratory data, emphasizing causal and aggravating factors and complaint evolution.
Chronic urticaria-angioedema occurred mainly in females (mean age: 35 years), but also in men (mean age: 32 years). White color and living in urban areas also predominated. There was no preferential time for symptoms to appear, and nighttime was the most commonly reported time for clinical worsening. Around half of the patients had urticaria associated with angioedema. There were no associated factors in most of the cases, and stress was the most commonly reported aggravating factor. The cause was ascertained in 37.6% of our cases. The mean duration of follow-up was 11.7 months. Around 60% of the patients evolved with the problem under control, 32% improved, 9% had no change in dermatological condition and only one patient worsened.
Chronic urticaria-angioedema was more common among middle-aged women. It is a long-term disease, and its cause was explained in about one-third of the patients. Half of the patients presented disease control after treatment lasting an average of approximately one year.
慢性荨麻疹-血管性水肿是一种常见的、病因多样的病症。目的是研究荨麻疹-血管性水肿的社会人口学和临床特征、病因及加重因素以及病情演变。
这是一项在圣保罗州立大学博图卡图医学院皮肤科门诊进行的描述性前瞻性研究。
对总共125例慢性荨麻疹-血管性水肿患者进行评估，以获取社会人口学数据、病史、皮肤科和一般临床数据以及实验室数据，重点关注病因及加重因素和病情演变。
慢性荨麻疹-血管性水肿主要发生在女性（平均年龄：35岁），男性也有（平均年龄：32岁）。白人及居住在城市地区的人也占多数。症状出现没有特定的优先时间，夜间是最常报告的临床症状加重时间。约一半的患者荨麻疹与血管性水肿相关。大多数病例没有相关因素，压力是最常报告的加重因素。在我们的病例中，37.6%的病因得以确定。平均随访时间为11.7个月。约60%的患者病情得到控制，32%有所改善，9%的皮肤病状况没有变化，只有1例患者病情恶化。
慢性荨麻疹-血管性水肿在中年女性中更为常见。这是一种长期疾病，约三分之一的患者病因得以明确。约一半的患者在平均持续约一年的治疗后病情得到控制。
