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居住在斯里兰卡和挪威的斯里兰卡人的维生素D状况。

Vitamin D status in Sri Lankans living in Sri Lanka and Norway.

作者信息

Meyer Haakon E, Holvik Kristin, Lofthus Cathrine M, Tennakoon Sampath U B

机构信息

Institute of General Practice and Community Medicine, University of Oslo, Blindern, Oslo, Norway.

出版信息

Br J Nutr. 2008 May;99(5):941-4. doi: 10.1017/S0007114507844138.

Abstract

Vitamin D deficiency is common in non-Western immigrant groups living in Western countries. A comparison of vitamin D status in individuals who have emigrated and individuals who remain in their country of origin is needed in order to provide information about the effect of moving to northern latitudes. A total of 196 participants aged 30-60 years in a cross-sectional population-based study in Kandy, Sri Lanka (latitude 7 degrees north) and 242 Sri Lankans aged 31-60 years participating in a cross-sectional population-based study in Oslo, Norway (latitude 60 degrees north) were included in the analysis. All serum samples were analysed for serum 25-hydroxyvitamin D (s-25(OH)D) in the same laboratory. Sri Lankans living in Norway had substantially lower s-25(OH)D (mean 31.5 nmol/l) compared with those living in Sri Lanka (mean 54.2 nmol/l), and the prevalence of s-25(OH)D < 25 nmol/l was 9.3 times higher (95 % CI 4.4, 19.6) in Norway compared with Sri Lanka. In Sri Lanka there was a clear seasonal variation with the lowest s-25(OH)D levels in August-September and the highest levels in November-December. We conclude that vitamin D status among Sri Lankans living in Kandy, Sri Lanka was considerably higher than that among Sri Lankans living in Oslo, Norway. The low vitamin D status commonly observed in non-Western immigrant groups living at northern latitudes should not be regarded as normal levels for these groups. However, also in Sri Lanka we found a profound seasonal variation with the lowest levels in August and September after the Monsoon.

摘要

维生素D缺乏在生活在西方国家的非西方移民群体中很常见。为了提供有关迁移到高纬度地区影响的信息,需要对移民个体和留在原籍国的个体的维生素D状况进行比较。在斯里兰卡康提(北纬7度)进行的一项基于人群的横断面研究中,共有196名年龄在30至60岁之间的参与者,以及在挪威奥斯陆(北纬60度)进行的一项基于人群的横断面研究中,242名年龄在31至60岁之间的斯里兰卡人被纳入分析。所有血清样本均在同一实验室分析血清25-羟基维生素D(s-25(OH)D)。与生活在斯里兰卡的人(平均54.2 nmol/l)相比,生活在挪威的斯里兰卡人的s-25(OH)D水平显著较低(平均31.5 nmol/l),且s-25(OH)D<25 nmol/l的患病率在挪威比在斯里兰卡高9.3倍(95%CI 4.4, 19.6)。在斯里兰卡,存在明显的季节性变化,8月至9月s-25(OH)D水平最低,11月至12月最高。我们得出结论,生活在斯里兰卡康提的斯里兰卡人的维生素D状况明显高于生活在挪威奥斯陆的斯里兰卡人。在高纬度地区生活的非西方移民群体中普遍观察到的低维生素D状况不应被视为这些群体的正常水平。然而,在斯里兰卡,我们也发现了季风过后8月和9月水平最低的显著季节性变化。

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