Meyer Haakon E, Holvik Kristin, Lofthus Cathrine M, Tennakoon Sampath U B
Institute of General Practice and Community Medicine, University of Oslo, Blindern, Oslo, Norway.
Br J Nutr. 2008 May;99(5):941-4. doi: 10.1017/S0007114507844138.
Vitamin D deficiency is common in non-Western immigrant groups living in Western countries. A comparison of vitamin D status in individuals who have emigrated and individuals who remain in their country of origin is needed in order to provide information about the effect of moving to northern latitudes. A total of 196 participants aged 30-60 years in a cross-sectional population-based study in Kandy, Sri Lanka (latitude 7 degrees north) and 242 Sri Lankans aged 31-60 years participating in a cross-sectional population-based study in Oslo, Norway (latitude 60 degrees north) were included in the analysis. All serum samples were analysed for serum 25-hydroxyvitamin D (s-25(OH)D) in the same laboratory. Sri Lankans living in Norway had substantially lower s-25(OH)D (mean 31.5 nmol/l) compared with those living in Sri Lanka (mean 54.2 nmol/l), and the prevalence of s-25(OH)D < 25 nmol/l was 9.3 times higher (95 % CI 4.4, 19.6) in Norway compared with Sri Lanka. In Sri Lanka there was a clear seasonal variation with the lowest s-25(OH)D levels in August-September and the highest levels in November-December. We conclude that vitamin D status among Sri Lankans living in Kandy, Sri Lanka was considerably higher than that among Sri Lankans living in Oslo, Norway. The low vitamin D status commonly observed in non-Western immigrant groups living at northern latitudes should not be regarded as normal levels for these groups. However, also in Sri Lanka we found a profound seasonal variation with the lowest levels in August and September after the Monsoon.
维生素D缺乏在生活在西方国家的非西方移民群体中很常见。为了提供有关迁移到高纬度地区影响的信息，需要对移民个体和留在原籍国的个体的维生素D状况进行比较。在斯里兰卡康提（北纬7度）进行的一项基于人群的横断面研究中，共有196名年龄在30至60岁之间的参与者，以及在挪威奥斯陆（北纬60度）进行的一项基于人群的横断面研究中，242名年龄在31至60岁之间的斯里兰卡人被纳入分析。所有血清样本均在同一实验室分析血清25-羟基维生素D（s-25(OH)D）。与生活在斯里兰卡的人（平均54.2 nmol/l）相比，生活在挪威的斯里兰卡人的s-25(OH)D水平显著较低（平均31.5 nmol/l），且s-25(OH)D<25 nmol/l的患病率在挪威比在斯里兰卡高9.3倍（95%CI 4.4, 19.6）。在斯里兰卡，存在明显的季节性变化，8月至9月s-25(OH)D水平最低，11月至12月最高。我们得出结论，生活在斯里兰卡康提的斯里兰卡人的维生素D状况明显高于生活在挪威奥斯陆的斯里兰卡人。在高纬度地区生活的非西方移民群体中普遍观察到的低维生素D状况不应被视为这些群体的正常水平。然而，在斯里兰卡，我们也发现了季风过后8月和9月水平最低的显著季节性变化。
